ArticleArthritis research & therapy2018
Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study.
Article in Arthritis research & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Racial-Ethnic Differences in Osteoarthritis Pain and Disability: A Meta-Analysis.The journal of pain · 2019Pooled it
- Evaluation of lumbar segmental motion using ultrasound imaging following common joint mobilization techniques.The Journal of manual & manipulative therapy · 2025Trial
- [Efficacy of hydrotherapy versus gym treatment in primary total knee prosthesis due to osteoarthritis: a randomized controlled trial].Anales del sistema sanitario de Navarra · 2021Trial
- Prevalence of musculoskeletal pain in relation to joint hypermobility among health science students in Kuwait: a cross-sectional study.Clinical rheumatology · 2026Article
- [Hypermobility-Importance in rheumatology].Zeitschrift fur Rheumatologie · 2025Review
- Clinical efficacy of traditional Chinese medicine compound on patients with knee osteoarthritis and its impact on inflammatory cytokine levels.Pakistan journal of medical sciences · 2025Article
- The Effectiveness of Preoperative Outpatient and Home Rehabilitation and the Impact on the Results of Hip Arthroplasty: Introductory Report.Healthcare (Basel, Switzerland) · 2024Article
- Hypermobility spectrum disorders: A review.Rheumatology and immunology research · 2023Article
- Does medial patellofemoral ligament reconstruction result in femoral tunnel enlargement? A systematic review.Knee surgery & related research · 2023Review
- Development of a personalized shared decision-making tool for knee osteoarthritis and user-testing with African American and Latina women.Journal of family medicine and primary care · 2022Article
- Correlation of muscle and bone parameters, daily function and participation in women with generalized joint hypermobility: a descriptive evaluation.Journal of musculoskeletal & neuronal interactions · 2022Article
- Pelvic Girdle Pain, Hypermobility Spectrum Disorder and Hypermobility-Type Ehlers-Danlos Syndrome: A Narrative Literature Review.Journal of clinical medicine · 2020Review
- Is the Association between Knee Injury and Knee Osteoarthritis Modified by the Presence of General Joint Hypermobility.Osteoarthritis and cartilage open · 2020Article
- Joint hypermobility is not positively associated with prevalent multiple joint osteoarthritis: a cross-sectional study of older adults.BMC musculoskeletal disorders · 2019Article
- Relationship of Joint Hypermobility with Ankle and Foot Radiographic Osteoarthritis and Symptoms in a Community-Based Cohort.Arthritis care & research · 2019Article
- Generalised joint hypermobility increases ACL injury risk and is associated with inferior outcome after ACL reconstruction: a systematic review.BMJ open sport & exercise medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundOsteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and its relationship with knee, hip, and lumbar spine OA by race (African American vs. Caucasian).
methodsData were from the Johnston County OA project, collected 2003-2010. GJH was defined as Beighton score ≥4. OA symptoms were defined as the presence of pain, aching, or stiffness on most days separately at the knee, hip, and lower back. Radiographic OA (rOA) of the knee or hip was defined as Kellgren-Lawrence grade 2-4. Lumbar spine rOA was disc space narrowing grade ≥1 and osteophyte grade ≥2 in ≥ 1 at the same lumbar level. Lumbar spine facet rOA was present in ≥ 1 lumbar levels. Separate logistic regression models stratified by race were used to examine the association between hypermobility and rOA or OA symptoms at each joint site, adjusting for age, sex, previous joint injury, and body mass index (BMI).
resultsOf 1987 participants, 1/3 were African-American and 2/3 were women (mean age 65 years, mean BMI 31 kg/m
conclusionsGeneral joint hypermobility was more common in Caucasians than African-Americans. Although there were no associations between hypermobility and rOA, the association between hypermobility and lower back symptoms may differ by race.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.