ArticleImmunity2018
The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation.
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Article in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.
0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
128 citing papers in PubMed, 197 citations in OpenAlex.
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- An early burst of cytokine production before the first cell division influences CD8 T cell differentiation.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Impact of disease-associated chromatin accessibility QTLs across immune cell types and contexts.Cell genomics · 2026Article
- Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential.bioRxiv : the preprint server for biology · 2026Article
- Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy.Cellular & molecular immunology · 2026Review
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- Identification of a PRDM1-regulated T cell network to regulate atherosclerotic plaque inflammation.Genome medicine · 2025Article
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68 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Dapeng WangDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.
Huitian DiaoDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.
Adam J GetzlerDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.
Walter RogalDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.
Megan A FrederickDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.
Justin MilnerDivision of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
Bingfei YuDivision of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
Shane CrottyDivision of Vaccine Discovery, The La Jolla Institute of Allergy and Immunology, La Jolla, CA, USA; Division of Infectious Diseases, Department of Medicine, UCSD School of Medicine, La Jolla, CA, USA.
Ananda W GoldrathDivision of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
Matthew E PipkinDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA. Electronic address: mpipkin@scripps.edu.
Scripps Research Institute · USUniversity of California San Diego · USLa Jolla Institute for Immunology · US
Funding
TF regulation of CD8 and CD4 T cell memory in both systemic and dermal infectionU19AI109976 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PETERS, BJOERN · 2014 to 2018
$10.5MT cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0MRegulation of nucleosome positions and transcription during CTL differentiationR01AI095634 · NIAID · SCRIPPS FLORIDA · PI PIPKIN, MATTHEW EUGENE · 2011 to 2015
$2.4MNIAID NIH HHS R01 AI095634NIAID NIH HHS R37 AI067545NIAID NIH HHS U19 AI109976
Abstract
T cell receptor (TCR) stimulation of naive CD8
Indexed as
AnimalsBinding SitesCell DifferentiationCell LineCell ProliferationChlorocebus aethiopsChromatinCore Binding Factor Alpha 3 SubunitCricetinaeEnzyme ActivationFemaleHumansImmunologic MemoryInterferon Regulatory Factor-4Interferon Regulatory FactorsMaleChromatinCore Binding Factor Alpha 3 SubunitInterferon Regulatory Factor-4Interferon Regulatory FactorsPositive Regulatory Domain I-Binding Factor 1Receptors, Antigen, T-CellRunx3 protein, mousechromatin accessibilityepigenetic reprogrammingmemory CTL differentiationpioneer transcription factorRunx-family transcription factor
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.