Evidence map›Paper›PMID 29669101›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2018

Time Trend in Persistent Cognitive Decline: Results From the Longitudinal Aging Study Amsterdam.

Tessa N van den Kommer, Dorly J H Deeg, Wiesje M van der Flier, Hannie C Comijs

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Secular trends in cognitive trajectories of diverse older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2019
    Article
  10. Article
  11. Introduction to a Supplement on Population Level Trends in Dementia: Causes, Disparities, and Projections.The journals of gerontology. Series B, Psychological sciences and social sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tessa N van den KommerGGZinGeest, Amsterdam, The Netherlands.
Dorly J H DeegDepartment of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands.
Wiesje M van der FlierVUmc Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands.
Hannie C ComijsGGZinGeest, Amsterdam, The Netherlands.

Funding

Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joelle Abramowitz · 1999 to 2026
$23.2M
NIA NIH HHS P30 AG012846
6 · The paper itself

Abstract

Objective: To study time trends in the incidence of persistent cognitive decline (PCD), and whether an increase or decrease is explained by changes in well-known risk factors of dementia. Method: Data from the Longitudinal Aging Study Amsterdam over a period of 20 years were used. Subsamples of 65-88 year-olds were selected at 7 waves, with numbers ranging from 1,800 to 1,165. Within-person change in cognitive functioning was used to determine PCD. In logistic generalized estimating equations (GEE), time (0, 3, 6, 9, 13, and 16 years) was the main predictor of 3-year PCD incidence. Explanatory variables were lagged one wave before incident PCD and included in separate models. Results: PCD incidence was 2.5% at first, and 3.4% at last follow-up. GEE showed a positive time trend for PCD incidence [Exp(B)time = 1.042; p < .001]. None of the explanatory variables significantly changed the strength of the regression coefficient of linear time. Higher age, lower education, diabetes mellitus, smoking, lower body-mass index, and lower level of physical activity were associated with higher incidence of PCD. Conclusion: An increase in PCD incidence over time was found. Although well-known risk factors were associated with incidence per se, they did not explain the increase in incidence of PCD.

Indexed as

AgingSeverity of Illness IndexAgedAged, 80 and overCognitive DysfunctionDementiaDisease ProgressionFemaleHumansIncidenceLongitudinal StudiesMaleNetherlandsRisk AssessmentRisk FactorsTime Factors

Identifiers

PMID29669101
PMCPMC6283313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.