ArticleCerebral cortex (New York, N.Y. : 1991)2019
Densities and Laminar Distributions of Kv3.1b-, PV-, GABA-, and SMI-32-Immunoreactive Neurons in Macaque Area V1.
Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Calcium-Binding Protein Expression Cannot Serve as a General Classifier for GABAergic Neurons in the Macaque Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Neuropixels reveal laminar microcircuit organization in monkey V1 in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Neuropixels reveal structure-function relationships in monkey V1bioRxiv : the preprint server for biology · 2025Article
- Developmental dynamics of marmoset prefrontal cortical SST and PV interneuron networks highlight primate-specific features.Development (Cambridge, England) · 2025Article
- Article
- Developmental dynamics of the prefrontal cortical SST and PV interneuron networks: Insights from the monkey highlight human-specific features.bioRxiv : the preprint server for biology · 2024Article
- Laminar specificity and coverage of viral-mediated gene expression restricted to GABAergic interneurons and their parvalbumin subclass in marmoset primary visual cortex.bioRxiv : the preprint server for biology · 2024Article
- Circuit dynamics of superficial and deep CA1 pyramidal cells and inhibitory cells in freely-moving macaques.bioRxiv : the preprint server for biology · 2024Article
- Neuronal composition of processing modules in human V1: laminar density for neuronal and non-neuronal populations and a comparison with macaque.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Comparison of orientation encoding across layers within single columns of primate V1 revealed by high-density recordings.Frontiers in neural circuits · 2024Article
- The neurochemistry of learning-driven sensory eye dominance plasticity.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- GABAergic inhibition in the human visual cortex relates to eye dominance.Scientific reports · 2021Article
- Article
- Fast and reversible neural inactivation in macaque cortex by optogenetic stimulation of GABAergic neurons.eLife · 2020Article
- Functional Clusters of Neurons in Layer 6 of Macaque V1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- A Quantitative Comparison of Inhibitory Interneuron Size and Distribution between Mouse and Macaque V1, Using Calcium-Binding Proteins.Cerebral cortex communications · 2020Article
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4 authors.
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Abstract
The Kv3.1b potassium channel subunit is associated with narrow spike widths and fast-spiking properties. In macaque primary visual cortex (V1), subsets of neurons have previously been found to be Kv3.1b-immunoreactive (ir) but not parvalbumin (PV)-ir or not GABA-ir, suggesting that they may be both fast-spiking and excitatory. This population includes Meynert cells, the large layer 5/6 pyramidal neurons that are also labeled by the neurofilament antibody SMI-32. In the present study, triple immunofluorescence labeling and confocal microscopy were used to measure the distribution of Kv3.1b-ir, non-PV-ir, non-GABA-ir neurons across cortical depth in V1, and to determine whether, like the Meynert cells, other Kv3.1b-ir excitatory neurons were also SMI-32-ir pyramidal neurons. We found that Kv3.1b-ir, non-PV-ir, non-GABA-ir neurons were most prevalent in the M pathway-associated layers 4 Cα and 4B. GABAergic neurons accounted for a smaller fraction (11%) of the total neuronal population across layers 1-6 than has previously been reported. Of Kv3.1b-ir neurons, PV expression reliably indicated GABA expression. Kv3.1b-ir, non-PV-ir neurons varied in SMI-32 coimmunoreactivity. The results suggest the existence of a heterogeneous population of excitatory neurons in macaque V1 with the potential for sustained high firing rates, and these neurons were particularly abundant in layers 4B and 4 Cα.
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