Evidence map›Paper›PMID 29668826›Full record

ReviewMemorias do Instituto Oswaldo Cruz2018

Variability in innate host immune responses to cryptococcosis.

Mariam Garelnabi, Robin C May

Abstract readReview
In one paragraph

Review in Memorias do Instituto Oswaldo Cruz, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. The hypervirulent Type-1/Type-17 phenotype ofInfection and immunity · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Importance of Clinical Isolates inJournal of fungi (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Animal Models ofFrontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mariam GarelnabiSchool of Biosciences, Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham, UK.
Robin C MaySchool of Biosciences, Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcosis is an invasive fungal disease caused by Cryptococcus neoformans and the closely related species C. gattii. The severe form of the disease, cryptococcal meningitis (CM), is rapidly fatal without treatment. Although typically a disease of immunocompromised (especially HIV-positive) individuals, there is growing awareness of cryptococcal disease amongst non-immunocompromised patients. Whilst substantial progress has been made in understanding the pathogenicity of C. neoformans in HIV patients, prospective data on cryptococcosis outside the context of HIV remains lacking. Below we review how innate immune responses vary between hosts depending on immunological status, and discuss risk factors and predictors of disease outcome in different groups.

Indexed as

AIDS-Related Opportunistic InfectionsCryptococcosisCryptococcus neoformansHumansImmunity, InnateImmunocompromised Host

Identifiers

PMID29668826
PMCPMC5909084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.