Evidence map›Paper›PMID 29668817›Full record

ReviewRevista de saude publica2018

Adverse events of vaccines and the consequences of non-vaccination: a critical review.

Luana Raposo de Melo Moraes Aps, Marco Aurélio Floriano Piantola, Sara Araujo Pereira, Julia Tavares de Castro, Fernanda Ayane de Oliveira Santos, Luís Carlos de Souza Ferreira

Open access · goldAbstract readReview
In one paragraph

Review in Revista de saude publica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Vaccines for preventing herpes zoster in older adults.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Vaccines for preventing herpes zoster in older adults.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Protective Immunity and New Vaccines for Lyme Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Spatial behavior of hepatitis A, MMR, and varicella vaccination coverage in the state of Minas Gerais, 2020.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Characterization and evaluation of the enzymatic activity of tetanus toxin submitted to cobalt-60 gamma radiation.The journal of venomous animals and toxins including tropical diseases · 2021
    Article
  16. Longitudinal profiling of the vaccination coverage in Brazil reveals a recent change in the patterns hallmarked by differential reduction across regions.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Luana Raposo de Melo Moraes ApsDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.
Marco Aurélio Floriano PiantolaDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.
Sara Araujo PereiraDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.
Julia Tavares de CastroCentro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brasil.
Fernanda Ayane de Oliveira SantosCentro de Imunologia, Instituto Adolfo Lutz, São Paulo, SP, Brasil.
Luís Carlos de Souza FerreiraDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.
Universidade de São Paulo · BRInstituto Adolfo Lutz · BRInstituto Butantan · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the risks related to vaccines and the impacts of non-vaccination on the world population.

methodsThis is a narrative review that has considered information present in the bibliographic databases NCBI-PubMed, Medline, Lilacs, and Scientific Electronic Library Online (SciELO), between November 2015 and November 2016. For the analysis of outbreaks caused by non-vaccination, we considered the work published between 2010 and 2016.

resultsWe have described the main components of the vaccines offered by the Brazilian public health system and the adverse events associated with these elements. Except for local inflammatory reactions and rare events, such as exacerbation of autoimmune diseases and allergies, no causal relationship has been demonstrated between the administration of vaccines and autism, Alzheimer's disease, or narcolepsy. On the other hand, the lack of information and the dissemination of non-scientific information have contributed to the reemergence of infectious diseases in several countries in the world and they jeopardize global plans for the eradication of these diseases.

conclusionsThe population should be well informed about the benefits of vaccination and health professionals should assume the role of disseminating truthful information with scientific support on the subject, as an ethical and professional commitment to society.

Indexed as

Medication AdherenceAdverse Drug Reaction Reporting SystemsBrazilFemaleHumansMaleNational Health ProgramsRisk FactorsVaccinationVaccinesVaccines

Identifiers

PMID29668817
PMCPMC5933943
OpenAlexW2796325751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.