Evidence map›Paper›PMID 29668538›Full record

Trial reportJournal of pediatric hematology/oncology2019

Central Nervous System Involvement of Rhabdomyosarcoma: A Single Institution Experience.

Daniel C Moreira, Margaret E Macy, Carrye R Cost, Brian S Greffe, Timothy P Garrington

Abstract readClinical Trial
In one paragraph

Trial report in Journal of pediatric hematology/oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 20 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel C MoreiraDepartment of Pediatric Oncology, University of Colorado Denver School of Medicine and Children's Hospital Colorado, Aurora, CO.
Margaret E Macy
Carrye R Cost
Brian S Greffe
Timothy P Garrington
University of Colorado Denver · USChildren's Hospital Colorado · US

Funding

Promoting Healthy Cancer Survivorship in Rural Colorado Primary Health Care PractR25CA160013 · NCI · UNIVERSITY OF COLORADO DENVER · PI GARRINGTON, TIMOTHY P, HODGSON, CAROL S · 2012 to 2016
$1.5M
NCI NIH HHS R25 CA160013
6 · The paper itself

Abstract

The incidence of central nervous system (CNS) involvement in patients with rhabdomyosarcoma (RMS) is low, and the outcome is dismal. We present a single institution analysis of CNS involvement of pediatric RMS. In 59 patients, the prevalence of CNS involvement was 11.9% (7 patients), higher than prior reports. Of the 6 deaths from disease, all had rapid progression, with a median survival of 14 days. The higher incidence could be secondary to treatment modifications or more sensitive detection. These findings are useful for decisions at the time of CNS involvement and could lead to modifications for future RMS clinical trials.

Indexed as

Central Nervous System NeoplasmsRhabdomyosarcomaAdolescentAdultChildChild, PreschoolDisease-Free SurvivalFemaleHumansMalePrevalenceRetrospective StudiesSurvival Rate

Identifiers

PMID29668538
PMCPMC6192856
OpenAlexW2799485255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.