ArticleJournal of neurophysiology2018
Local tuning biases in mouse primary visual cortex.
Article in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- A mouse model for cerebral/cortical visual impairment (CVI) impairs vision and disrupts the spatial frequency tuning of neurons in visual cortex.Experimental neurology · 2026Article
- Enhancing Experience-Dependent Plasticity Accelerates Vision Loss in a Murine Model of Retinitis Pigmentosa.Investigative ophthalmology & visual science · 2026Article
- A mouse model for cerebral/cortical visual impairment (CVI) impairs vision and disrupts the spatial frequency tuning of neurons in visual cortex.bioRxiv : the preprint server for biology · 2025Article
- Representational drift gates critical-period plasticity in mouse visual cortex.Current biology : CB · 2025Article
- Enhancing experience-dependent plasticity accelerates vision loss in a murine model of retinitis pigmentosa.bioRxiv : the preprint server for biology · 2025Article
- Article
- Circuit-Based Understanding of Fine Spatial Scale Clustering of Orientation Tuning in Mouse Visual Cortex.bioRxiv : the preprint server for biology · 2025Article
- Effects of COVID-19 on the contrast sensitivity.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Good vision without peripheries: behavioral and fMRI evidence.Scientific reports · 2024Article
- Microglia are dispensable for experience-dependent refinement of mouse visual circuitry.Nature neuroscience · 2024Article
- On the contrast response function of adapted neural populations.Journal of neurophysiology · 2024Article
- On the contrast response function of adapted neural populations.bioRxiv : the preprint server for biology · 2023Article
- Dynamic Recruitment of the Feedforward and Recurrent Mechanism for Black-White Asymmetry in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Monocular deprivation during the critical period alters neuronal tuning and the composition of visual circuitry.PLoS biology · 2023Article
- Luminance Contrast Shifts Dominance Balance between ON and OFF Pathways in Human Vision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Thalamocortical boutons cluster by ON/OFF responses in mouse primary visual cortex.Journal of neurophysiology · 2023Article
- Cortical mechanisms of visual brightness.Cell reports · 2022Article
- ON/OFF domains shape receptive field structure in mouse visual cortex.Nature communications · 2022Article
- Vision is required for the formation of binocular neurons prior to the classical critical period.Current biology : CB · 2021Article
- Spatial modulation of dark versus bright stimulus responses in the mouse visual system.Current biology : CB · 2021Article
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4 authors.
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Abstract
Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of the local image. Such a functional module is assumed to be replicated across primary visual cortex to provide a uniform representation of the image across the entire visual field. In contrast, it has been hypothesized that the tiling properties of ON- and OFF-center receptive fields in the retina, largely mirrored in the geniculate, may constrain cortical tuning at each location in the visual field. This model predicts the existence of local biases in tuning that vary across the visual field and would prevent the cortex from developing a uniform, modular representation as postulated by the classic model. Here, we confirm the existence of local tuning biases in the primary visual cortex of the mouse, lending support to the notion that cortical tuning may be constrained by signals from the periphery. NEW & NOTEWORTHY Populations of cortical neurons responding to the same part of the visual field are shown to have similar tuning. Such local biases are consistent with the hypothesis that cortical tuning, in mouse primary visual cortex, is constrained by signals from the periphery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.