Evidence map›Paper›PMID 29668341›Full record

ArticleNanotoxicology2018

Silicon dioxide nanoparticle exposure affects small intestine function in an in vitro model.

Zhongyuan Guo, Nicole J Martucci, Yizhong Liu, Eusoo Yoo, Elad Tako, Gretchen J Mahler

Open access · greenAbstract read
In one paragraph

Article in Nanotoxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Article
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  7. Article
  8. Review
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  12. Article
  13. Study on the interaction ofFood chemistry: X · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Nanocomposites for Food Packaging Applications: An Overview.Nanomaterials (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhongyuan Guoa Department of Biomedical Engineering , Binghamton University , Binghamton , NY , USA.
Nicole J Martuccia Department of Biomedical Engineering , Binghamton University , Binghamton , NY , USA.
Yizhong Liua Department of Biomedical Engineering , Binghamton University , Binghamton , NY , USA.ORCID 0000-0003-3335-5628
Eusoo Yooa Department of Biomedical Engineering , Binghamton University , Binghamton , NY , USA.
Elad Takob Plant, Soil and Nutrition Laboratory , Agricultural Research Services, U.S. Department of Agriculture , Ithaca , NY , USA.ORCID 0000-0002-7856-5197
Gretchen J Mahlera Department of Biomedical Engineering , Binghamton University , Binghamton , NY , USA.ORCID 0000-0002-7286-8920
Binghamton University · USAgricultural Research Service · US

Funding

The effects of engineered nanoparticle ingestion on mineral absorption and smallR15ES022828 · NIEHS · STATE UNIVERSITY OF NY,BINGHAMTON · PI MAHLER, GRETCHEN · 2013 to 2013
$431k
NIEHS NIH HHS R15 ES022828
6 · The paper itself

Abstract

The use of nanomaterials to enhance properties of food and improve delivery of orally administered drugs has become common, but the potential health effects of these ingested nanomaterials remain unknown. The goal of this study is to characterize the properties of silicon dioxide (SiO

Indexed as

Caco-2 CellsCoculture TechniquesHT29 CellsHumansIntestinal MucosaIntestine, SmallNanoparticlesReactive Oxygen SpeciesSilicon DioxideReactive Oxygen SpeciesSilicon DioxideConsumer productsexposurefoodrisk assessmentSiO2

Identifiers

PMID29668341
PMCPMC6157813
OpenAlexW2801405338

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.