Evidence map›Paper›PMID 29668313›Full record

ArticleNutrition and cancer2018

Dietary Glycemic Load, Glycemic Index, and Carbohydrate Intake on the Risk of Lung Cancer among Men and Women in Shanghai.

Jiang-Wei Sun, Wei Zheng, Hong-Lan Li, Jing Gao, Gong Yang, Yu-Tang Gao, Nat Rothman, Qing Lan, Xiao-Ou Shu, Yong-Bing Xiang

Abstract read
In one paragraph

Article in Nutrition and cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiang-Wei Suna State Key Laboratory of Oncogene and Related Genes , Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.
Wei Zhengc Division of Epidemiology, Vanderbilt Epidemiology Center , Vanderbilt University Medicine Center , Nashville , Tennessee , USA.
Hong-Lan Lia State Key Laboratory of Oncogene and Related Genes , Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.
Jing Gaoa State Key Laboratory of Oncogene and Related Genes , Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.
Gong Yangc Division of Epidemiology, Vanderbilt Epidemiology Center , Vanderbilt University Medicine Center , Nashville , Tennessee , USA.
Yu-Tang Gaob Department of Epidemiology , Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.
Nat Rothmand Division of Cancer Epidemiology and Genetics , National Cancer Institute , Rockville , Maryland , USA.
Qing Land Division of Cancer Epidemiology and Genetics , National Cancer Institute , Rockville , Maryland , USA.
Xiao-Ou Shuc Division of Epidemiology, Vanderbilt Epidemiology Center , Vanderbilt University Medicine Center , Nashville , Tennessee , USA.
Yong-Bing Xianga State Key Laboratory of Oncogene and Related Genes , Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.

Funding

Cohort Study of Cancer inhibitory Factors in MenR01CA082729 · NCI · VANDERBILT UNIVERSITY · PI SHU, XIAO-OU · 2001 to 2011
$6.3M
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
Shanghai Men's Health StudyUM1CA173640 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU · 2013 to 2017
$4.9M
Cancer Risk Reduction and Diet: A Cohort Study of WomenR37CA070867 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2009 to 2013
$4.7M
NCI NIH HHS R01 CA082729NCI NIH HHS R37 CA070867NCI NIH HHS UM1 CA173640NCI NIH HHS UM1 CA182910NIH HHS R01 CA082729NIH HHS R37 CA070867NIH HHS UM1 CA173640NIH HHS UM1 CA182910
6 · The paper itself

Abstract

To investigate the potential influence of dietary glycemic index, glycemic load, or carbohydrate intake and lung cancer risk in Shanghai. We prospectively investigated the associations among 130,858 participants in the Shanghai Women's and Men's Health Studies. Diet was assessed using validated food-frequency questionnaires. Lung cancer cases were ascertained through annual record linkage and every 2-3 years in-home visits. Cox proportional hazard regression model was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). After excluding the first 2 years of observation, 1312 participants (including 649 women and 663 men) developed lung cancer during an average follow-up of 14.8 (SD: 2.0) years for SWHS and 9.3 (SD: 1.6) years for SMHS. In multivariable analysis, no statistically significant associations were observed between glycemic index, glycemic load, and carbohydrate intake and lung cancer risk for either men or women. Similar results were observed among never smokers, and participants without history of lung disease, diabetes, or hypertension. Stratification by body mass index or menopause status also did not alter the findings. Our studies, conducted in populations who habitually have high-carbohydrate diets, provide no evidence that dietary glycemic index, glycemic load, or carbohydrate intake is associated with lung cancer risk.

Indexed as

Glycemic IndexGlycemic LoadAdultChinaDietDietary CarbohydratesFemaleHumansLung NeoplasmsMaleMiddle AgedMultivariate AnalysisProspective StudiesRisk FactorsDietary Carbohydrates

Identifiers

PMID29668313
PMCPMC6527441

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.