Evidence map›Paper›PMID 29667724›Full record

ArticleJournal of clinical laboratory analysis2018

Relationship between C-reactive protein/albumin ratio and coronary artery disease severity in patients with stable angina pectoris.

Yavuz Karabağ, Metin Çağdaş, Ibrahim Rencuzogullari, Süleyman Karakoyun, İnanç Artaç, Doğan İliş, Eray Atalay, Mahmut Yesin, Mustafa Ozan Gürsoy, Ibrahim Halil Tanboğa

Abstract read
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Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

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  16. Relationship Between CRP/ALB Ratio and Severity of Coronary Artery Lesions in Hypertensive Patients with Acute Myocardial Infarction.Medical science monitor : international medical journal of experimental and clinical research · 2025
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yavuz KarabağDepartment of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.ORCID http://orcid.org/0000-0002-8156-315X
Metin ÇağdaşDepartment of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
Ibrahim RencuzogullariDepartment of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
Süleyman KarakoyunDepartment of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
İnanç ArtaçDepartment of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
Doğan İlişDepartment of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
Eray AtalayDepartment of Internal Medicine, Kafkas University Medical Faculty, Kars, Turkey.
Mahmut YesinDepartment of Cardiology, Kars Harakani State Hospital, Kars, Turkey.
Mustafa Ozan GürsoyDepartment of Cardiology, İzmir Katip Çelebi University, İzmir, Turkey.
Ibrahim Halil TanboğaDepartment of Cardiology, Ataturk University Medical Faculty, Erzurum, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyntax score (SS), which is an angiographic tool used in grading the complexity of coronary artery disease (CAD), has prognostic importance in coronary artery disease (CAD) and provides important information regarding selection of revascularization strategy. C-reactive protein (CRP) and albumin are indicators of inflammation, and high levels of them are associated with high SS. We aimed to investigate whether baseline CRP to albumin ratio C-Reactive Protein/Albumin Ratio (CAR), an easily available and novel inflammatory marker, is associated with SS.

methodA total 403 consecutive patients with stabile angina pectoris, who underwent coronary angiography for suspected CAD from January 2015 to June 2016, were classified into two groups, low SS (≤22) and intermediate-high SS (>22).

resultsC-Reactive Protein/Albumin Ratio was significantly higher in patients with intermediate-high SS group (P < .001). In multivariate regression analysis, CAR remained an independent predictor of intermediate-high SS group together with hypertension and LDL. The predictive performance of CAR, CRP, and albumin was compared by ROC curve analysis. CAR surpassed CRP and albumin in predicting intermediate-high SS group. CAR >6.3 predicted an intermediate-high SS with sensitivity and specificity of 86.8% and 43.4%, respectively.

conclusionC-Reactive Protein/Albumin Ratio was more tightly associated with the complexity and severity of CAD than CRP and albumin alone and was found to be an independent predictor for intermediate-high SS group.

Indexed as

Coronary Artery DiseaseAgedAngina, StableBiomarkersC-Reactive ProteinFemaleHumansMaleMiddle AgedROC CurveSerum AlbuminSeverity of Illness IndexBiomarkersC-Reactive ProteinSerum Albuminalbumincoronary artery disease severityC-reactive proteinC-reactive protein/albumin ratiostable angina pectorissyntax score

Identifiers

PMID29667724
PMCPMC6816976

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.