Evidence map›Paper›PMID 29667615›Full record

ReviewAsian journal of andrology

Vitamin D in prostate cancer.

Donald L Trump, Jeanny B Aragon-Ching

Open access · goldAbstract readReview
In one paragraph

Review in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.

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  18. Serum vitamin D and PSA in elderly men in Amirkola.Caspian journal of internal medicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donald L TrumpInova Schar Cancer Institute, Inova Health System, Fairfax, VA 22037, USA.
Jeanny B Aragon-ChingInova Schar Cancer Institute, Inova Health System, Fairfax, VA 22037, USA.
Inova Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signaling through the vitamin D receptor has been shown to be biologically active and important in a number of preclinical studies in prostate and other cancers. Epidemiologic data also indicate that vitamin D signaling may be important in the cause and prognosis of prostate and other cancers. These data indicate that perturbation of vitamin D signaling may be a target for the prevention and treatment of prostate cancer. Large studies of vitamin D supplementation will be required to determine whether these observations can be translated into prevention strategies. This paper reviews the available data in the use of vitamin D compounds in the treatment of prostate cancer. Clinical data are limited which support the use of vitamin D compounds in the management of men with prostate cancer. However, clinical trials guided by existing preclinical data are limited.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCalcifediolCalcitriolClinical Trials as TopicErgocalciferolsHumansMaleProstatic NeoplasmsSignal TransductionVitamin DVitamin D Deficiency1 alpha-hydroxyergocalciferolCalcifediolCalcitriolErgocalciferolsparicalcitolVitamin DandrogensCYP24A1inflammationprostate cancervitamin D analogs

Identifiers

PMID29667615
PMCPMC5952478
OpenAlexW2802593900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.