Evidence map›Paper›PMID 29667564›Full record

ArticleInternational psychogeriatrics2018

The recency ratio as predictor of early MCI.

Davide Bruno, Rebecca L Koscik, John L Woodard, Nunzio Pomara, Sterling C Johnson

Abstract read
In one paragraph

Article in International psychogeriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Abnormal Forgetting Rate from the Recency Portion of a Word-List in Patients with Subjective Cognitive Decline.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
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  3. Predicting CDR status over 36 months with a recall-based digital cognitive biomarker.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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  9. The recency ratio assessed by story recall is associated with cerebrospinal fluid levels of neurodegeneration biomarkers.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
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  13. CSF α-synuclein correlates with CSF neurogranin in late-life depression.The International journal of neuroscience · 2021
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  16. Predicting Early Mild Cognitive Impairment With Free Recall: The Primacy of Primacy.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2020
    Article
  17. The recency ratio is related to CSF amyloid beta 1-42 levels in MCI-AD.International journal of geriatric psychiatry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Davide BrunoSchool of Natural Science and Psychology,Liverpool John Moores University,Liverpool,UK;Department of Psychology,Liverpool Hope University,Liverpool,UK.
Rebecca L KoscikWisconsin Alzheimer's Institute,School of Medicine and Public Health,University of Wisconsin-Madison,Madison,WI,USA.
John L WoodardDepartment of Psychology,Wayne State University,Detroit,Michigan,USA.
Nunzio PomaraNathan Kline Institute for Psychiatric Research,Orangeburg,New York,USA;Department of Psychiatry,School of Medicine,New York University,New York City,New York,USA.
Sterling C JohnsonGeriatric Research Education and Clinical Center,Wm. S. Middleton Veterans Hospital,Madison,Wisconsin,USA.

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Wisconsin Registry for Alzheimer's Prevention: Sex Differences in DNA MethylationR01AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Nathaniel Ark Chin, Sterling C Johnson · 2007 to 2026
$35.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Wisconsin Registry for Alzheimer's PreventionRF1AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, STERLING C · 2018 to 2018
$18.8M
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NIA NIH HHS R01 AG027161NIA NIH HHS RF1 AG027161
6 · The paper itself

Abstract

ABSTRACTObjectives:Individuals with Alzheimer's disease (AD) present poor immediate primacy recall accompanied by intact or exaggerated recency, which then tends to decline after a delay. Bruno et al. (Journal of Clinical and Experimental Neuropsychology, Vol. 38, 2016, pp. 967-973) have shown that higher ratio scores between immediate and delayed recency (i.e. the recency ratio; Rr) are associated with cognitive decline in high-functioning older individuals. We tested whether Rr predicted conversion to early mild cognitive impairment (early MCI) from a cognitively healthy baseline.

designData were analyzed longitudinally with binomial regression. Baseline scores were used to predict conversion to early MCI after approximately nine years.

settingData were collected at the Wisconsin Registry of Alzheimer's Prevention, in Madison, Wisconsin.

participantsFor the study, 427 individuals were included in the analysis; all participants were 50 years of age or older and cognitively intact at baseline, and were native English speakers. MEASUREMENTS: Memory data were collected using the Rey's Auditory Verbal Learning Test, and the early MCI diagnosis was obtained via consensus conference.

resultsOur results showed that higher Rr scores are correlated with greater risk of later early MCI diagnosis, and this association is independent of total recall performance.

conclusionsRr is an emerging cognitive marker of cognitive decline.

Indexed as

Memory, Short-TermMental RecallAgedAlzheimer DiseaseCognitionCognitive DysfunctionFemaleHumansMaleMiddle AgedWisconsinAlzheimer's diseaseearly MCIrecency ratioserial position

Identifiers

PMID29667564
PMCPMC6193873

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.