Evidence map›Paper›PMID 29667360›Full record

ArticleJournal of diabetes investigation2019

Menstrual and reproductive factors and type 2 diabetes risk: The Japan Public Health Center-based Prospective Study.

Akiko Nanri, Tetsuya Mizoue, Mitsuhiko Noda, Atsushi Goto, Norie Sawada, Shoichiro Tsugane, Japan Public Health Center-based Prospective Study (JPHC Study) Group

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Association of Parity with Type 2 Diabetes Mellitus in Japan.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Akiko NanriDepartment of Food and Health Sciences, International College of Arts and Sciences, Fukuoka Women's University, Fukuoka, Japan.ORCID http://orcid.org/0000-0002-7487-8778
Tetsuya MizoueDepartment of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Mitsuhiko NodaDepartment of Endocrinology and Diabetes, Saitama Medical University, Saitama, Japan.
Atsushi GotoEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Norie SawadaEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Shoichiro TsuganeEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Japan Public Health Center-based Prospective Study (JPHC Study) Group
Fukuoka Women's University · JPNational Center for Global Health and Medicine · JPSaitama Medical University · JP

Funding

AMED-WISEGrant-in-Aid for Cancer Research from the Ministry of Health, Labor and Welfare of JapanNational Cancer Center Research and Development Fund
6 · The paper itself

Abstract

AIMS/

introductionMenstrual and reproductive factors, including age at menarche, parity and breast-feeding, have been linked to type 2 diabetes risk. We prospectively investigated the association between these factors and type 2 diabetes risk in a large Japanese cohort. MATERIALS AND

methodsParticipants were 37,511 women aged 45-75 years who participated in the baseline (1990-1993), second (1995-1998) and third surveys (2000-2003) of the Japan Public Health Center-based Prospective Study, and who had no history of diabetes at the second survey. Menstrual and reproductive history was ascertained using questionnaires at the baseline and second surveys. Odds ratios of self-reported, physician-diagnosed type 2 diabetes over the 5-year period from the second survey were estimated using logistic regression.

resultsAt the third survey, 513 new cases of type 2 diabetes were self-reported. The odds ratios of type 2 diabetes tended to increase with the number of parity, after adjustment for covariates other than body mass index (P for trend = 0.029). The multivariable-adjusted odds ratios of type 2 diabetes for women with three or more births was 1.56 (95% confidence interval 0.96-2.53) compared with those who were nulliparous. The association between parity and type 2 diabetes risk was attenuated after additional adjustment for body mass index (P for trend = 0.12). No factors other than parity were significantly associated with type 2 diabetes risk.

conclusionsHigher parity might be associated with an increased risk of type 2 diabetes among Japanese women, partly through increasing bodyweight.

Indexed as

MenstruationReproductionAgedAsian PeopleBody Mass IndexDiabetes Mellitus, Type 2FemaleHumansJapanMiddle AgedParityPregnancyProspective StudiesRisk FactorsSurveys and QuestionnairesJapaneseParityType 2 diabetes

Identifiers

PMID29667360
PMCPMC6319489
OpenAlexW2802214148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.