Evidence map›Paper›PMID 29667216›Full record

ArticleClinical cardiology2018

Nationwide Routine-Data Analysis of Sex Differences in Outcome of Acute Myocardial Infarction.

Eva Freisinger, Susanne Sehner, Nasser M Malyar, Anna Suling, Holger Reinecke, Karl Wegscheider

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. OECD indicator 'AMI 30-day mortality' is neither comparable between countries nor suitable as indicator for quality of acute care.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  6. Article
  7. Article
  8. Predicting Return to Work Following Myocardial Infarction: A Prospective Longitudinal Cohort Study.International journal of environmental research and public health · 2022
    Article
  9. Sex Difference in the Case Fatality of Older Myocardial Infarction Patients.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Does gender influence the outcome of ischemic heart disease?Przeglad menopauzalny = Menopause review · 2019
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eva FreisingerDivision of Vascular Medicine, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.ORCID http://orcid.org/0000-0002-4409-3179
Susanne SehnerInstitute of Medical Biometry and Epidemiology, Universitatsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany.
Nasser M MalyarDivision of Vascular Medicine, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.
Anna SulingInstitute of Medical Biometry and Epidemiology, Universitatsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany.
Holger ReineckeDivision of Vascular Medicine, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany.
Karl WegscheiderInstitute of Medical Biometry and Epidemiology, Universitatsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany.
Universität Hamburg · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women have been reported to suffer from impaired outcome after acute myocardial infarction (AMI). The aim of our study was to determine the impact of sex and age on utilization of inpatient healthcare and outcome in patients with AMI (STEMI and NSTEMI) in a real-life setting. We performed a routine-data-based analysis of 203 106 nationwide inpatients hospitalized with STEMI and NSTEMI, focusing on sex differences regarding risk constellation, treatments, and in-hospital outcome. A logistic regression model was designed to evaluate the use of coronary angiography and interventions and their sex-related impact on mortality (within 30 days). Compared with males, female STEMI patients (25 146, vs 52 965 males) were older and had a higher incidence of diabetes mellitus (27.4% vs 20.6%), heart failure (32.8% vs 26.2%), and chronic kidney disease (19.1% vs 13.5%, respectively; all P < 0.05), and had higher observed in-hospital mortality (STEMI, 16.9% vs 9.9%; NSTEMI, 11.7% vs 8.7%). Females were less likely to receive coronary angiography in STEMI in the age groups <60 and ≥ 80 years (odds ratio: 0.8, 95% confidence interval: 0.76-0.83, P < 0.05), despite similar mortality risk reduction. Estimated overall in-hospital mortality showed no differences with respect to sex in STEMI for age groups 40 to 79 years. However, females age ≥ 80 years had slightly higher in-hospital mortality after adjustment. The increased observed in-hospital mortality in females was attributed to the impact of more unfavorable risk and age distribution. Coronary angiography was associated with lower in-hospital mortality; particularly, older females were less frequently treated.

Indexed as

Population SurveillanceAdultAgedAged, 80 and overAge DistributionAge FactorsCoronary AngiographyFemaleGermanyHospital MortalityHumansIncidenceMaleMiddle AgedMyocardial InfarctionPrognosisAcute Coronary CareAcute Coronary SyndromeEpidemiologyGenderWomen

Identifiers

PMID29667216
PMCPMC6489736
OpenAlexW2800582977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.