Evidence map›Paper›PMID 29667118›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2018

ACMT Position Statement: Alternative or Contingency Countermeasures for Acetylcholinesterase Inhibiting Agents.

Andrew Stolbach, Vikhyat Bebarta, Michael Beuhler, Shaun Carstairs, Lewis Nelson, Michael Wahl, Paul M Wax, Charles McKay

Open access · bronzeAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Andrew StolbachJohns Hopkins University, Baltimore, MD, USA. positionstatements@acmt.net.
Vikhyat BebartaUniversity of Colorado School of Medicine, Denver, CO, USA.
Michael BeuhlerCarolinas Poison Center, Charlotte, NC, USA.
Shaun CarstairsUniversity of California, San Diego, CA, USA.
Lewis NelsonRutgers New Jersey Medical School, Newark, NJ, USA.
Michael WahlIllinois Poison Center, Chicago, IL, USA.
Paul M WaxUniversity of Texas Southwestern Medical School, Dallas, TX, USA.
Charles McKayUniversity of Connecticut School of Medicine, Farmington, CT, USA.
Johns Hopkins University · USRutgers, The State University of New Jersey · USThe University of Texas Southwestern Medical Center · USUniversity of California, San Diego · USUniversity of Colorado Denver · USUniversity of Connecticut · USWashington Poison Center · US

Funding

United States Department of Homeland Security ACMT/DHS Contract number HSHQDC-14-R-00102. United States Department of Homeland Security ACMT/DHS Contract number HSHQDC-14-R-00102.
6 · The paper itself

Abstract

First responders and health care providers must prepare to provide care for patients poisoned by acetylcholinesterase (AchE) inhibitor chemical warfare agents or pesticides. However, pre-deployed medical countermeasures (MCMs) may not be sufficient due to production and delivery interruption, rapid depletion of contents during a response, expiration of MCM components, or lack of local availability of approved MCMs. To augment supplies of community-based and forward-deployed nerve agent countermeasures, the American College of Medical Toxicology (ACMT) supports several strategies: (1) The use of expired atropine, diazepam, and pralidoxime auto-injectors and vials if non-expired drugs are unavailable; and (2) Investigation, development, and identification of alternative countermeasures-commonly stocked drugs that are not approved for nerve agent poisoning but are in the same therapeutic class as approved drugs.

Indexed as

Societies, MedicalToxicologyChemical Warfare AgentsCholinesterase InhibitorsCholinesterase ReactivatorsDrug StorageHumansOrganophosphate PoisoningPoisoningUnited StatesChemical Warfare AgentsCholinesterase InhibitorsCholinesterase ReactivatorsAcetylcholinesterase inhibitorsAtropineCountermeasuresExpiration datePralidoxime

Identifiers

PMID29667118
PMCPMC6097966
OpenAlexW2799749845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.