Evidence map›Paper›PMID 29667110›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018

Gender affects prognosis of methicillin-resistant Staphylococcus aureus bacteremia differently depending on the severity of underlying disease.

Chang Kyung Kang, Yee Gyung Kwak, Youngmi Park, Kyoung-Ho Song, Eu Suk Kim, Sook-In Jung, Kyung-Hwa Park, Wan Beom Park, Nam Joong Kim, Young Keun Kim and 8 more

Abstract read
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
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  9. A Prospective Cohort Study of Durations ofAntimicrobial agents and chemotherapy · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Chang Kyung KangSeoul National University Bundang Hospital, Seongnam, South Korea.
Yee Gyung KwakInje University Ilsan Paik Hospital, Goyang, South Korea.
Youngmi ParkSeoul National University Bundang Hospital, Seongnam, South Korea.
Kyoung-Ho SongSeoul National University Bundang Hospital, Seongnam, South Korea.
Eu Suk KimSeoul National University Bundang Hospital, Seongnam, South Korea.
Sook-In JungChonnam National University Hospital, Gwangju, South Korea.
Kyung-Hwa ParkChonnam National University Hospital, Gwangju, South Korea.
Wan Beom ParkSeoul National University Hospital, Seoul, South Korea.
Nam Joong KimSeoul National University Hospital, Seoul, South Korea.
Young Keun KimYonsei University Wonju College of Medicine, Wonju, South Korea.
Hee-Chang JangChonnam National University Hwasun Hospital, Hwasun, South Korea.
Shinwon LeePusan National University Hospital, Busan, South Korea.
Jae Hyun JeonInje University Haeundae Paik Hospital, Busan, South Korea.
Ki Tae KwonDaegu Fatima Hospital, Daegu, South Korea.
Chung-Jong KimEhwa Womans University Hospital, Seoul, South Korea.
Yeon-Sook KimChungnam National University School of Medicine, Daejeon, Republic of Korea. alice@cnuh.co.kr.
Hong Bin KimSeoul National University Bundang Hospital, Seongnam, South Korea. hbkimmd@snu.ac.kr.ORCID http://orcid.org/0000-0001-6262-372X
Korea INfectious Diseases (KIND) study group
Seoul National University Bundang Hospital · KRYonsei University · KRDaegu Fatima Hospital · KRSeoul National University Hospital · KRChonnam National University Hospital · KRChungnam National University · KRInje University Haeundae Paik Hospital · KRPusan National University Hospital · KR

Funding

National Research Foundation of Korea 2016H1C3A1903202Seoul National University Bundang Hospital 02-2017-003
6 · The paper itself

Abstract

We aimed to elucidate the potential impact of gender on prognosis of Staphylococcus aureus bacteremia (SAB). We analyzed SAB cases prospectively collected over an 8-year period at 11 hospitals in Korea. SAB-related mortality was pre-defined as a death within 30 days from the onset of SAB without other apparent cause of death. The effect of gender on SAB-related mortality was examined in the entire cohort and in subgroups stratified according to methicillin resistance and Charlson's comorbidity-weighted index (CCWI) score. Those factors independently associated to SAB-related mortality were explored. Among 1974 eligible cases, SAB-related mortality rates in male and female were 21.2% (259/1224) and 21.9% (164/750), respectively (P = 0.786). The SAB-related mortality rate was independently higher in male than that in female in CCWI score ≤ 3 methicillin-resistant SAB (MRSAB) group (15.9 vs. 6.2%; aOR 3.65, 95% CI 1.46-9.13; P = 0.006) while the association tended to be inverse when CCWI score rises. Interaction between CCWI score and gender to MRSAB-related mortality was significant in multivariate analysis (aOR 0.85, 95% CI 0.74-0.96; P = 0.011). There was no significant interaction between gender and CCWI in entire SAB or methicillin-susceptible SAB cohorts. Gender may affect clinical outcomes of MRSAB differently depending on the severity of underlying disease.

Indexed as

AgedAnti-Bacterial AgentsBacteremiaCohort StudiesCross InfectionFemaleHospitalsHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedPrognosisRepublic of KoreaSeverity of Illness IndexSex FactorsStaphylococcal InfectionsAnti-Bacterial AgentsBacteremiaGenderMortalityMRSAUnderlying disease

Identifiers

PMID29667110
OpenAlexW2799469304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.