Evidence map›Paper›PMID 29667078›Full record

ArticleThe international journal of cardiovascular imaging2018

Impact of different coarctation therapies on aortic stiffness: phase-contrast MRI study.

Michal Schäfer, Gareth J Morgan, Max B Mitchell, Michael Ross, Alex J Barker, Kendall S Hunter, Brian Fonseca, Michael DiMaria, Daniel Vargas, D Dunbar Ivy and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Cardiovascular imaging 2018 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2019
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Michal SchäferDivision of Cardiology, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, 13123 East 16th Avenue, Aurora, CO, 80045-2560, USA. michal.schafer@ucdenver.edu.ORCID http://orcid.org/0000-0002-1794-3262
Gareth J MorganDivision of Cardiology, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, 13123 East 16th Avenue, Aurora, CO, 80045-2560, USA.
Max B MitchellDivision of Congenital Heart Surgery, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Michael RossDivision of Congenital Heart Surgery, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Alex J BarkerDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Kendall S HunterDepartment of Bioengineering, College of Engineering and Applied Sciences, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Brian FonsecaDivision of Cardiology, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, 13123 East 16th Avenue, Aurora, CO, 80045-2560, USA.
Michael DiMariaDivision of Cardiology, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, 13123 East 16th Avenue, Aurora, CO, 80045-2560, USA.
Daniel VargasDepartment of Radiology, University of Colorado Hospital, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
D Dunbar IvyDivision of Cardiology, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, 13123 East 16th Avenue, Aurora, CO, 80045-2560, USA.
Neil WilsonDivision of Cardiology, Heart Institute, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, 13123 East 16th Avenue, Aurora, CO, 80045-2560, USA.
Lorna P BrowneDepartment of Radiology, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Children's Hospital Colorado · USNorthwestern University · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Hospital · US

Funding

Hemodynamic Loading of the Left Ventricle and Aorta in Aortic Valve DiseaseK25HL119608 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BARKER, ALEXANDER J. · 2014 to 2018
$819k
6 · The paper itself

Abstract

Coarctation of the aorta has been associated with increased thoracic aortic stiffness in adolescents and young adults. However, the effects of different therapeutic strategies on aortic stiffness in a young population is unknown. This study aimed to non-invasively assess aortic stiffness between different repair or intervention strategies in patients with coarctation of the aorta. Forty-nine coarctation patients who underwent either surgery (n = 26), balloon angioplasty (n = 14), or stent implantation (n = 12), and 26 age- and size-matched normotensive healthy controls underwent evaluation of thoracic aortic stiffness and flow hemodynamics via phase-contrast cardiac magnetic resonance. In children who had undergone surgical repair or balloon angioplasty, ascending aortic stiffness was increased when measured via pulse wave velocity (PWV) when compared to normal controls (all P < 0.05). Furthermore, ascending aortic distensibility and relative area change (RAC) was significantly lower in surgically and balloon treated groups (both P < 0.01). Stiffness (PWV), distensibility, and RAC in the ascending aorta were not statistically different between stented patients and controls. The ascending aorta of children following surgical repair or balloon angioplasty demonstrated signs of elevated stiffness, whereas those treated by stent implantation showed no difference in stiffness markers when compared to normal controls.

Indexed as

AdolescentAortaAortic CoarctationChildCross-Sectional StudiesEchocardiographyFemaleHumansMagnetic Resonance ImagingMalePredictive Value of TestsPulse Wave AnalysisRetrospective StudiesShear StrengthStress, MechanicalVascular StiffnessAortic coarctationCMRFlow imagingStiffness

Identifiers

PMID29667078
OpenAlexW2801023960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.