ArticleClinical research in cardiology : official journal of the German Cardiac Society2018
Inflammation and the risk of atrial high-rate episodes (AHREs) in patients with cardiac implantable electronic devices.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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28 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Association between atrial fibrillation and Helicobacter pylori.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Pooled it
- Characteristics of patients with atrial high rate episodes detected by implanted defibrillator and resynchronization devices.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022Trial
- Subclinical atrial fibrillation: Implications of recent trials for guideline updates?World journal of cardiology · 2026Review
- Predictors for Device-Detected Subclinical Atrial Fibrillation: An Up-to-Date Narrative Review.Journal of clinical medicine · 2026Review
- Clinical relevance and management of atrial high-rate episodes: a narrative review.Archivos de cardiologia de Mexico · 2025Review
- Impact of malnutrition on long-term atrial high-rate episodes, atrial fibrillation, and mortality in octogenarians with dual-chamber pacemakers.Aging clinical and experimental research · 2025Article
- Article
- Editorial to "The incidence and risk factors of atrial high-rate episodes in patients with a dual-chamber pacemaker".Journal of arrhythmia · 2024Article
- The incidence and risk factors of atrial high-rate episodes in patients with a dual-chamber pacemaker.Journal of arrhythmia · 2024Article
- The impact of the right heart cavities echocardiographic features on atrial-high rate episodes.The international journal of cardiovascular imaging · 2024Article
- A review of chemotherapeutic drugs-induced arrhythmia and potential intervention with traditional Chinese medicines.Frontiers in pharmacology · 2024Review
- Connecting atrial fibrillation to digestive neoplasms: exploring mediation via ischemic stroke and heart failure in Mendelian randomization studies.Frontiers in oncology · 2024Article
- Monocyte/High-Density Lipoprotein Ratio Is Associated with Atrial High-Rate Episodes within One Year Detected by Cardiac Implantable Electronic Devices.Brazilian journal of cardiovascular surgery · 2023Article
- Atrial high-rate episodes intensify RScientific reports · 2023Article
- Galectin-3, Inflammation, and the Risk of Atrial High-Rate Episodes in Patients with Dual Chamber Pacemakers.International journal of molecular sciences · 2023Article
- Clinical characteristics and management of immune checkpoint inhibitor-related cardiotoxicity: A single-center experience.Frontiers in cardiovascular medicine · 2023Article
- Identifying At-Risk Patients for Sustained Atrial High-Rate Episodes Using the CJournal of the American Heart Association · 2021Article
- Effect of antidiabetic drugs on the risk of atrial fibrillation: mechanistic insights from clinical evidence and translational studies.Cellular and molecular life sciences : CMLS · 2021Review
- Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation.Frontiers in cardiovascular medicine · 2021Article
- HATCH Score and Left Atrial Size Predict Atrial High-Rate Episodes in Patients With Cardiac Implantable Electronic Devices.Frontiers in cardiovascular medicine · 2021Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAtrial high-rate episodes (AHREs) are associated with an increased risk of developing atrial fibrillation and thromboembolism. The characteristics of 'real world' patients developing AHREs are poorly known.
methodsWe included 496 consecutive patients with cardiac implantable electronic devices (CIEDs). Primary endpoint was occurrence of AHREs, defined as > 175 bpm and lasting > 5 min, in a median follow-up of 16.5 (IQR 3.9-38.6) months (1082.4 patient-years). We also tested the predictive value of clinical risk scores for AHREs.
resultsMean age was 68.8 ± 14.0 years, and 35.5% were women; AHREs were recorded in 173 patients [34.7%, 16.0%/year, 95% confidence interval (CI) 13.7-18.6]. Multivariable Cox regression analysis showed that age [hazard ratio (HR) 1.020, 95% CI 1.004-1.035, p = 0.011], prior AF (HR 3.521, 95% CI 2.831-5.206, p < 0.001), white cell count (HR 1.039, 95% CI 1.007-1.072, p = 0.016) and high C reactive protein (CRP; HR 1.039, 95% CI 1.021-2.056, p = 0.038) were independently associated with AHREs. ROC curve analysis showed that the APPLE score (C statistic 0.53, 95% CI 0.48-0.59; p = 0.296) ALARMEc score (C statistic 0.51, 95% CI 0.44-0.57; p = 0.810) were non-significantly associated with AHRE. Similar results were obtained for CHADS
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