Evidence map›Paper›PMID 29666991›Full record

Observational studyEuropean radiology2018

Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography.

Joost R C Lameijer, Angela Mp Coolen, Adri C Voogd, Luc J Strobbe, Marieke W J Louwman, Dick Venderink, Vivian C Tjan-Heijnen, Lucien E M Duijm

Erratum issuedAbstract readObservational Study
In one paragraph

Observational study in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Joost R C LameijerDepartment of Radiology, Catharina Hospital, Michelangelolaan 2, 5623EJ, Eindhoven, The Netherlands. joostlameijer@gmail.com.ORCID http://orcid.org/0000-0002-1783-500X
Angela Mp CoolenDepartment of Radiology, Elisabeth-Tweesteden Hospital (ETZ), Hilvarenbeekseweg 60, 5022, GC, Tilburg, The Netherlands.
Adri C VoogdDepartment of Epidemiology, Maastricht University, P Debyelaan 1, 6229, HA, Maastricht, The Netherlands.
Luc J StrobbeDepartment of Radiology, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532, SZ, Nijmegen, The Netherlands.
Marieke W J LouwmanDepartment of Research, Netherlands Comprehensive Cancer Organization (IKNL), PO Box 19079, 3501, DB, Utrecht, The Netherlands.
Dick VenderinkDepartment of Radiology, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532, SZ, Nijmegen, The Netherlands.
Vivian C Tjan-HeijnenDepartment of Internal Medicine, Division of Medical Oncology, GROW Maastricht University Medical Centre, PO Box 5800, 6202, AZ, Maastricht, The Netherlands.
Lucien E M DuijmDepartment of Radiology, Canisius Wilhelmina Hospital, Weg door Jonkerbos 100, 6532, SZ, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the frequency and characteristics of contralateral, non-recalled breast abnormalities following recall at screening mammography.

methodsWe included a series of 130,338 screening mammograms performed between 1 January 2014 and 1 January 2016. During the 1-year follow-up, clinical data were collected for all recalls. Screening outcome was determined for recalled women with or without evaluation of contralateral breast abnormalities.

resultsOf 3,995 recalls (recall rate 3.1%), 129 women (3.2%) underwent assessment of a contralateral, non-recalled breast abnormality. Most lesions were detected at clinical mammography and/or breast tomosynthesis (101 women, 78.3%). The biopsy rate was similar for recalled lesions and contralateral, non-recalled lesions, but the positive predictive value of biopsy was higher for recalled lesions (p = 0.01). A comparable proportion of the recalled lesions and contralateral, non-recalled lesions were malignant (p = 0.1). The proportion of ductal carcinoma in situ was similar for both groups, as well as invasive cancer characteristics and type of surgical treatment.

conclusionsAbout 3% of recalled women underwent evaluation of contralateral, non-recalled breast lesions. Evaluation of the contralateral breast after recall is important as we found that 15.5% of contralateral, non-recalled lesions were malignant. Contralateral cancers and screen-detected cancers show similar characteristics, stage and surgical treatment. KEY POINTS: • 3% of recalled women underwent evaluation of contralateral, non-recalled lesions • One out of seven contralateral, non-recalled lesions was malignant • A contralateral cancer was diagnosed in 0.5% of recalls • Screen-detected cancers and non-recalled, contralateral cancers showed similar histological characteristics • Tumour stage and surgical treatment were similar for both groups.

Indexed as

Early Detection of CancerMammographyMass ScreeningAgedBiopsy, Large-Core NeedleBreastBreast NeoplasmsFemaleFollow-Up StudiesHumansMiddle AgedProspective StudiesBreastBreast neoplasmsMammographyMass screeningRadiology

Identifiers

PMID29666991
PMCPMC6132700

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.