Evidence map›Paper›PMID 29666892›Full record

ArticleThe Journal of membrane biology2018

Using Liprotides to Deliver Cholesterol to the Plasma Membrane.

Henriette S Frislev, Janni Nielsen, Jesper Nylandsted, Daniel Otzen

Abstract read
PubMed Publisher
In one paragraph

Article in The Journal of membrane biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Henriette S FrislevInterdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark.
Janni NielsenInterdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark.
Jesper NylandstedMembrane Integrity Group, Cell Death and Metabolism Unit, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark. jnl@cancer.dk.
Daniel OtzenInterdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark. dao@inano.au.dk.
Aarhus University · DKDanish Cancer Society · DK

Funding

Teknologi og Produktion, Det Frie Forskningsråd DFF-4005-00479
6 · The paper itself

Abstract

Cholesterol (chol) is important in all mammalian cells as a modulator of membrane fluidity. However, its low solubility is a challenge for controlled delivery to membranes. Here we introduce a new tool to deliver chol to membranes, namely, liprotides, i.e., protein-lipid complexes composed of a fatty acid core decorated with partially denatured protein. We focus on liprotides prepared by incubating Ca

Indexed as

beta-CyclodextrinsCell MembraneCholesterolLactalbuminOleic Acidbeta-CyclodextrinsCholesterolLactalbuminmethyl-beta-cyclodextrinOleic AcidCholesterolCytotoxicityLiprotidesMembrane

Identifiers

PMID29666892
OpenAlexW2801729241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.