ReviewAnnals of translational medicine2018
Ground glass opacities management in the lung cancer screening era.
Review in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- The impact of segmentectomy versus lobectomy on pulmonary function in patients with non-small-cell lung cancer: a meta-analysis.Journal of cardiothoracic surgery · 2022Pooled it
- The Epidemiology of Ground Glass Opacity Lung Adenocarcinoma: A Network-Based Cumulative Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Trial
- Safety and efficacy of a novel transbronchial radiofrequency ablation system for lung tumours: One year follow-up from the first multi-centre large-scale clinical trial (BRONC-RFII).Respirology (Carlton, Vic.) · 2025Trial
- Diagnosis and selection of surgical approaches for synchronous multiple primary lung cancer: a narrative review.Journal of thoracic disease · 2026Review
- Decoding Malignant Lung Ground Glass Opacities: A Radiologic-Pathologic Study From Pure to Semi-Solid Lesions.Thoracic cancer · 2026Article
- Multiple Primary Lung Cancers in Surgical Patients: Revisiting Martini and Melamed 50 Years Later.Cancers · 2026Article
- Patient selection and clinical generalizability of intraoperative lung ultrasound-guided decision-making in robotic thoracic surgery.Updates in surgery · 2026Article
- Translational development of an SGLT2-targeted near-infrared contrast agent for intraoperative imaging of early-stage lung cancer.EJNMMI research · 2026Article
- ERS Congress 2025: highlights from the Thoracic Surgery and Lung Transplantation Assembly.ERJ open research · 2026Article
- Short-term outcomes of robot-assisted and conventional lung segmentectomy: a single-center retrospective comparative study.Fukushima journal of medical science · 2026Article
- Development of a CT-based comprehensive model with deep learning for differentiating pathological types of pulmonary ground-glass nodules.Frontiers in medicine · 2026Article
- Tumor-educated platelet RNA as a diagnostic biomarker for ground-glass opacity-related lung adenocarcinoma.Translational lung cancer research · 2025Article
- Translating premalignant biology to accelerate non-small-cell lung cancer interception.Nature reviews. Cancer · 2025Review
- Clinical analysis of incidental discovery of pulmonary nodules with computed tomography: a retrospective cohort study.Journal of thoracic disease · 2025Article
- An early lung cancer diagnosis model for non-smokers incorporating ct imaging analysis and circulating genetically abnormal cells (CACs).BMC cancer · 2025Article
- Radiomics of Vascular Structures in Pulmonary Ground-glass Nodules: A Predictor of InvasivenessCurrent medical imaging · 2025Article
- Clinical Versus Pathological Staging in Patients with Resected Ground Glass Pulmonary Lesions.Diagnostics (Basel, Switzerland) · 2024Article
- The value of thoracoscopic ultrasound for the localization of ground-glass opacities with incomplete lung collapse in video-assisted thoracoscopic surgery.Quantitative imaging in medicine and surgery · 2024Article
- An AI-Based Low-Risk Lung Health Image Visualization Framework Using LR-ULDCT.Journal of imaging informatics in medicine · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary ground glass opacity (GGO) is becoming an important clinical dilemma in oncology as its diagnosis in clinical practice is increasing due to the introduction of low dose computed tomography (CT) scan and screening. The incidence of cancer in GGO has been reported as high as 63%. The purpose of this manuscript is to review best available evidence papers on management of GGO in lung cancer to address the following questions: (I) how to correlate CT findings with malignancy; (II) when and who operate? (III) how to perform intraoperative detection of intrapulmonary GGO? (IV) wedge, segmentectomy or lobectomy? Taking a cue from a clinical scenario, a review on PubMed was conducted. The words search included: "Lung ground glass opacity". The research was limited to human and adults. We considered all published articles from 1990 to April 2017, which reported on at least sufficient data, to be eligible. The literature search was limited to articles in English. A total of 1,211 articles have been found. Interestingly, while in 1991, only one paper was published on low-dose high-resolution CT, in 2016, 126 papers have been published. Most cited and recent papers have been chosen for discussion. Many recent papers have been published from Asian groups. It is clearly not possible to conclude from these data what is the best strategy for GGO in the lung cancer screening era. Certainly, when there is uncertainty, personal opinion and experience should not influence decision making, on the contrary decision should be taken by a multidisciplinary team.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.