ArticleFrontiers in cell and developmental biology2018
PLCζ Induced Ca
Article in Frontiers in cell and developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- PIP5K1A-PIP2-RhoA Signaling Orchestrates Membrane Remodeling during Early Porcine Embryo Development.International journal of biological sciences · 2026Article
- Rescuing Fertilization Failure in ICSI: A Narrative Review of Calcium Ionophore Activation, PLCζ Testing, and Embryo Morphokinetics.Biomedicines · 2025Review
- Phospholipase Cζ, the Molecular Spark of Fertilization and Male Infertility: Insights from Bench to Bedside.Medicina (Kaunas, Lithuania) · 2025Review
- Kappa opioids inhibit spinal output neurons to suppress itch.Science advances · 2024Article
- Molecular Mechanism of Oocyte Activation in Mammals: Past, Present, and Future Directions.Biomolecules · 2024Review
- The signal that stimulates mammalian embryo development.Frontiers in cell and developmental biology · 2024Review
- Sperm induce a secondary increase in ATP levels in mouse eggs that is independent of Ca2+ oscillations.The Biochemical journal · 2023Article
- ZneLife · 2023Article
- Phospholipase C Zeta 1 (PLCZ1): The Function and Potential for Fertility Assessment and In Vitro Embryo Production in Cattle and Horses.Veterinary sciences · 2023Review
- Sperm-Induced CaCells · 2023Review
- Identification of a convergent spinal neuron population that encodes itch.bioRxiv : the preprint server for biology · 2023Article
- ZnbioRxiv : the preprint server for biology · 2023Article
- Where are all the egg genes?Frontiers in cell and developmental biology · 2023Review
- Deletion of TRPV3 and CaV3.2 T-type channels in mice undermines fertility and Ca2+ homeostasis in oocytes and eggs.Journal of cell science · 2021Article
- The role of ATP in the differential ability of Sr2+ to trigger Ca2+ oscillations in mouse and human eggs.Molecular human reproduction · 2021Article
- A Novel Assisted Oocyte Activation Method Improves Fertilization in Patients With Recurrent Fertilization Failure.Frontiers in cell and developmental biology · 2021Article
- Modulators of calcium signalling at fertilization.Open biology · 2020Review
- CaCold Spring Harbor perspectives in biology · 2019Review
- The eggstraordinary story of how life begins.Molecular reproduction and development · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Egg activation at fertilization in mammalian eggs is caused by a series of transient increases in the cytosolic free Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.