Evidence map›Paper›PMID 29666757›Full record

ArticlePeerJ2018

Evolution of dopamine receptors: phylogenetic evidence suggests a later origin of the DRD

Juan C Opazo, Kattina Zavala, Soledad Miranda-Rottmann, Roberto Araya

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Juan C OpazoInstituto de Ciencias Ambientales y Evolutivas, Universidad Austral de Chile, Valdivia, Chile.
Kattina ZavalaInstituto de Ciencias Ambientales y Evolutivas, Universidad Austral de Chile, Valdivia, Chile.
Soledad Miranda-RottmannDepartment of Neurosciences, Faculty of Medicine, University of Montreal, Montreal, Canada.
Roberto ArayaDepartment of Neurosciences, Faculty of Medicine, University of Montreal, Montreal, Canada.
Austral University of Chile · CLUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine receptors are integral membrane proteins whose endogenous ligand is dopamine. They play a fundamental role in the central nervous system and dysfunction of dopaminergic neurotransmission is responsible for the generation of a variety of neuropsychiatric disorders. From an evolutionary standpoint, phylogenetic relationships among the DRD

Indexed as

Dopamine receptorsGene family evolutionNeuroscienceWhole genome duplications

Identifiers

PMID29666757
PMCPMC5900934
OpenAlexW2797464049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.