Observational studyPain research & management2018
Early Factors Associated with the Development of Chronic Pain in Trauma Patients.
Observational study in Pain research & management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors to Persistent Pain Following Musculoskeletal Injuries: A Systematic Literature Review.International journal of environmental research and public health · 2022Pooled it
- Feasibility of a Hybrid Web-Based and In-Person Self-management Intervention Aimed at Preventing Acute to Chronic Pain Transition After Major Lower Extremity Trauma (iPACT-E-Trauma): A Pilot Randomized Controlled Trial.Pain medicine (Malden, Mass.) · 2019Trial
- Relationships among peri-traumatic circulating endocannabinoids and long-term, negative outcomes following traumatic injury.Psychopharmacology · 2026Article
- Cost-effectiveness of paramedic administered ketamine compared to morphine for the management of acute severe pain from traumatic injury.Cost effectiveness and resource allocation : C/E · 2026Article
- Exploring chronic pain: demographic and social determinants of health insights in Maine.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Predictors of chronic pain, chronic opioid use and neuropathic pain in Ukrainian military patients with isolated thoracic injuries sustained during the Russia-Ukraine conflict: a single-centre prospective observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Observational
- Paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN): a randomised, double-blind, phase 3 trial.The Lancet regional health. Europe · 2025Article
- Traumatic Exposure and PTSD Symptoms in a Sample From a Tertiary Pain Clinic.Pain practice : the official journal of World Institute of Pain · 2025Observational
- The Synergistic Effect of Acute Traumatic Brain Injury and Spinal Cord Injury on the Development of Chronic Pain: A Populational Cohort Study on Neurotrauma Patients in Canada.Topics in spinal cord injury rehabilitation · 2025Observational
- Increased Incidence of Depression and Chronic Pain in Traumatic Spinal Cord Injury Patients With Pre-Injury Alcohol Use Disorder: Longitudinal Analysis of Insurance Claim Database.Neurotrauma reports · 2024Article
- Randomised controlled trial of analgesia for the management of acute severe pain from traumatic injury: study protocol for the paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN).Scandinavian journal of trauma, resuscitation and emergency medicine · 2023Article
- Racial and Ethnic Disparities in Chronic Pain following Traumatic Injury.Pain medicine (Malden, Mass.) · 2023Article
- Opioid Poisoning and Opioid Use Disorder in Older Trauma Patients.Clinical interventions in aging · 2020Article
- Chronic Pain following Chest Trauma: Prevalence, Associated Factors, and Psychosocial Impact.Pain research & management · 2020Observational
- Pain severity at emergency department discharge as a predictor for chronification of pain.Pain reportsArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To identify factors, available at the time of trauma admission, associated with the development of chronic pain to allow testing of preventive approaches. Methods: In a retrospective observational cohort study, we included all patients ≥ 18 years old admitted for injury in 57 adult trauma centers in the province of Quebec (Canada) between 2004 and 2014. Chronic pain was defined as follows: treated in a chronic pain clinic, diagnosed with chronic pain, or received at least 2 prescriptions of chronic pain medications 3 to 12 months postinjury. Results: A total of 95,134 patients were retained for analysis. Mean age was 59.8 years (±21.7), and 52% were men. The causes of trauma were falls (63%) and motor vehicle accidents (22%). We identified 14,518 patients (15.3%; 95% CI: 15.1-15.5) who developed chronic pain. After controlling for confounding factors, the variables associated with chronic pain were spinal cord injury (OR = 3.9; 95% CI: 3.4-4.6), disc-vertebra trauma (OR = 1.6; 95% CI: 1.5-1.7), history of alcoholism (OR = 1.4; 95% CI: 1.2-1.7), history of anxiety (OR = 1.4; 95% CI: 1.2-1.5), history of depression (OR = 1.3; 95% CI: 1.1-1.4), and being female (OR = 1.3; 95% CI: 1.2-1.3). The area under the receiving operating characteristic curve derived from the model was 0.80. Conclusions: We identified risk factors present on hospital admission that can predict trauma patients who will develop chronic pain. These factors should be prospectively validated.
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