ArticleFrontiers in human neuroscience2018
Local Use-Dependent Sleep in Wakefulness Links Performance Errors to Learning.
Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- The effects of non-invasive transcutaneous auricular vagus nerve stimulation on resting-state delta oscillation: a randomized, double-blinded, sham-control trial.Scientific reports · 2025Trial
- Pharmacological Manipulations of Physiological Arousal and Sleep-Like Slow Waves Modulate Sustained Attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Trial
- Invertebrate brains as diversified models for understanding sleep mechanisms and function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Post-Learning Offline Pauses Support Consolidation Beyond the Mind-Wandering State.Clocks & sleep · 2026Article
- Slow wave canonical activity deviation concept: Toward a slow wave-based EEG-fMRI reference map for health-associated network function.iScience · 2026Article
- Sleep-Like Slow Waves during Wakefulness Mediate Attention and Vigilance Difficulties in Adult Attention-Deficit/Hyperactivity Disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- A bistable stochastic model quantifies performance degradation during sleep deprivation.Sleep · 2025Article
- Sleep on it: exploring the psychology of sleep amidst contemporary challenges.Scientific reports · 2024Article
- Prolonged exertion of self-control causes increased sleep-like frontal brain activity and changes in aggressivity and punishment.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Behavioral and Electrophysiological Markers of Attention Fluctuations in Children with Hypersomnolence.Journal of clinical medicine · 2024Article
- Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain.PLoS computational biology · 2024Article
- Intracortical mechanisms of single pulse electrical stimulation (SPES) evoked excitations and inhibitions in humans.Scientific reports · 2024Article
- Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain.bioRxiv : the preprint server for biology · 2024Article
- An integrative sensor of body states: how the mushroom body modulates behavior depending on physiological context.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Review
- Targeted dream incubation at a distance: the development of a remote and sensor-free tool for incubating hypnagogic dreams and mind-wandering.Frontiers in sleep · 2024Article
- Wake slow waves in focal human epilepsy impact network activity and cognition.Nature communications · 2023Article
- Local extracellular KProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Getting a Good Night's Sleep: Associations Between Sleep Duration and Parent-Reported Sleep Quality on Default Mode Network Connectivity in Youth.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023Article
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4 authors.
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Abstract
Sleep and wakefulness are no longer to be considered as discrete states. During wakefulness brain regions can enter a sleep-like state (off-periods) in response to a prolonged period of activity (local use-dependent sleep). Similarly, during nonREM sleep the slow-wave activity, the hallmark of sleep plasticity, increases locally in brain regions previously involved in a learning task. Recent studies have demonstrated that behavioral performance may be impaired by off-periods in wake in task-related regions. However, the relation between off-periods in wake, related performance errors and learning is still untested in humans. Here, by employing high density electroencephalographic (hd-EEG) recordings, we investigated local use-dependent sleep in wake, asking participants to repeat continuously two intensive spatial navigation tasks. Critically, one task relied on previous map learning (Wayfinding) while the other did not (Control). Behaviorally awake participants, who were not sleep deprived, showed progressive increments of delta activity only during the learning-based spatial navigation task. As shown by source localization, delta activity was mainly localized in the left parietal and bilateral frontal cortices, all regions known to be engaged in spatial navigation tasks. Moreover, during the Wayfinding task, these increments of delta power were specifically associated with errors, whose probability of occurrence was significantly higher compared to the Control task. Unlike the Wayfinding task, during the Control task neither delta activity nor the number of errors increased progressively. Furthermore, during the Wayfinding task, both the number and the amplitude of individual delta waves, as indexes of neuronal silence in wake (off-periods), were significantly higher during errors than hits. Finally, a path analysis linked the use of the spatial navigation circuits undergone to learning plasticity to off periods in wake. In conclusion, local sleep regulation in wakefulness, associated with performance failures, could be functionally linked to learning-related cortical plasticity.
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