Evidence map›Paper›PMID 29666426›Full record

ArticleScientific reports2018

Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice.

Siiri E Iismaa, Ming Li, Scott Kesteven, Jianxin Wu, Andrea Y Chan, Sara R Holman, John W Calvert, Ahtesham Ul Haq, Amy M Nicks, Nawazish Naqvi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  10. Mechanism-Based Cardiac Regeneration Strategies in Mammals.Frontiers in cell and developmental biology · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Morphological and clinical aspects of acute postmyocardial remodeling in patients with pre-existing hypertrophy.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Siiri E IismaaDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Ming LiDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Scott KestevenDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Jianxin WuDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Andrea Y ChanDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Sara R HolmanDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
John W CalvertDepartment of Surgery, Emory University School of Medicine, Atlanta, GA, 30308, USA.
Ahtesham Ul HaqDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Amy M NicksDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Nawazish NaqviDepartment of Medicine, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Ahsan HusainDepartment of Medicine, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Michael P FeneleyDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia.
Robert M GrahamDivision of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Sydney, NSW 2010, Australia. b.graham@victorchang.edu.au.
Victor Chang Cardiac Research Institute · AUEmory University · USUNSW Sydney · AUWenzhou Medical University · CN

Funding

The Vascular Chymase-Angiotensin II SystemR01HL079040 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HUSAIN, AHSAN · 2006 to 2014
$3.0M
Development of the Postnatal HeartR01HL127726 · NHLBI · EMORY UNIVERSITY · PI HUSAIN, AHSAN, NAQVI, NAWAZISH ALI · 2016 to 2019
$1.6M
NHLBI NIH HHS R01 HL079040NHLBI NIH HHS R01 HL127726
6 · The paper itself

Abstract

We have previously demonstrated that adult transgenic C57BL/6J mice with CM-restricted overexpression of the dominant negative W

Indexed as

AnimalsCardiomegalyDisease Models, AnimalHypertrophy, Left VentricularMaleMice, Inbred C57BLMice, TransgenicMutationMyocardial InfarctionMyocardiumProto-Oncogene Proteins c-kitVentricular Dysfunction, LeftProto-Oncogene Proteins c-kit

Identifiers

PMID29666426
PMCPMC5904135
OpenAlexW2801330673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.