Evidence map›Paper›PMID 29666285›Full record

ArticlemBio2018

Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during

Richard C White, Felizza F Gunderson, Jessica Y Tyson, Katherine H Richardson, Theo J Portlock, James A Garnett, Nicholas P Cianciotto

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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  11. Protein sociology of ProA, Mip and other secreted virulence factors at theFrontiers in cellular and infection microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Richard C WhiteDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Felizza F GundersonDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Jessica Y TysonDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Katherine H RichardsonDepartment of Chemistry and Biochemistry, Queen Mary University of London, London, United Kingdom.
Theo J PortlockDepartment of Chemistry and Biochemistry, Queen Mary University of London, London, United Kingdom.
James A GarnettDepartment of Chemistry and Biochemistry, Queen Mary University of London, London, United Kingdom j.garnett@qmul.ac.uk n-cianciotto@northwestern.edu.
Nicholas P CianciottoDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA j.garnett@qmul.ac.uk n-cianciotto@northwestern.edu.
Northwestern University · USQueen Mary University of London · GB

Funding

TRAINING PROGRAM IN IMMUNOLOGY &MOLECULAR PATHOGENESIST32AI007476 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Edward Benjamin Thorp · 1996 to 2026
$6.6M
TYPE II SECRETION AND LEGIONELLA PNEUMOPHILA INFECTIONR01AI043987 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 1999 to 2017
$4.8M
Medical Research Council MR/M009920/1NIAID NIH HHS R01 AI043987NIAID NIH HHS T32 AI007476
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acanthamoeba castellaniiAcyltransferasesAminopeptidasesBacterial ProteinsCrystallography, X-RayGene DeletionLegionella pneumophilaProtein ConformationSubstrate SpecificityType II Secretion SystemsAcyltransferasesAminopeptidasesBacterial Proteinsglycerophospholipid-cholesterol acyltransferaseType II Secretion SystemsAcanthamoebaacyltransferaseaminopeptidaseintracellular infectionLegionella pneumophilaLegionnaires' diseaseproteasetype II secretion

Identifiers

PMID29666285
PMCPMC5904407
OpenAlexW2795382526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.