Evidence map›Paper›PMID 29666272›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Human

Renuka Kadirvelraj, Jeong-Yeh Yang, Justin H Sanders, Lin Liu, Annapoorani Ramiah, Pradeep Kumar Prabhakar, Geert-Jan Boons, Zachary A Wood, Kelley W Moremen

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 47 citations in OpenAlex.

  1. Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter forJournal of the American Chemical Society · 2026
    Article
  2. Article
  3. Iterative Bump-and-hole engineering creates a bioorthogonal reporter forbioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. The Role of Glycans in Human Immunity-A Sweet Code.Molecules (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Structural glycobiology - from enzymes to organelles.Biochemical Society transactions · 2025
    Review
  9. An overview of proteinFrontiers in plant science · 2025
    Review
  10. Article
  11. Article
  12. Immunometabolism (Cobham, Surrey) · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors.Biochimica et biophysica acta. General subjects · 2022
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Renuka KadirvelrajDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.
Jeong-Yeh YangComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602-4712.
Justin H SandersDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.
Lin LiuComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602-4712.
Annapoorani RamiahComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602-4712.
Pradeep Kumar PrabhakarComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602-4712.
Geert-Jan BoonsComplex Carbohydrate Research Center, University of Georgia, Athens, GA 30602-4712.
Zachary A WoodDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602; zaw@uga.edu moremen@uga.edu.
Kelley W MoremenDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602; zaw@uga.edu moremen@uga.edu.ORCID 0000-0003-1768-582X
University of Georgia · US

Funding

TR&D3. Approaches to Proteoglycan Function at Biochemical and Cellular LevelsP41GM103390 · NIGMS · UNIVERSITY OF GEORGIA · PI MOREMEN, KELLEY W. · 2012 to 2019
$14.5M
Recombinant Production of Glycosylation Enzymes for Biochem/Structural StudiesP01GM107012 · NIGMS · UNIVERSITY OF GEORGIA · PI PRESTEGARD, JAMES H. · 2013 to 2017
$7.5M
Origin of N-Glycan Site-Specific HeterogeneityR01GM130915 · NIGMS · UNIVERSITY OF GEORGIA · PI KANNAN, NATARAJAN, MOREMEN, KELLEY W. · 2019 to 2022
$3.4M
The role of intrinsic disorder in the allosteric regulation of human UGDHR01GM114298 · NIGMS · UNIVERSITY OF GEORGIA · PI WOOD, ZACHARY ARTHUR · 2015 to 2025
$2.7M
NIGMS NIH HHS P01 GM107012NIGMS NIH HHS P41 GM103390NIGMS NIH HHS R01 GM114298NIGMS NIH HHS R01 GM130915
6 · The paper itself

Abstract

Asn-linked oligosaccharides are extensively modified during transit through the secretory pathway, first by trimming of the nascent glycan chains and subsequently by initiating and extending multiple oligosaccharide branches from the trimannosyl glycan core. Trimming and branching pathway steps are highly ordered and hierarchal based on the precise substrate specificities of the individual biosynthetic enzymes. A key committed step in the synthesis of complex-type glycans is catalyzed by

Indexed as

Protein FoldingHumansN-AcetylglucosaminyltransferasesProtein DomainsUridine Diphosphate N-Acetylglucosaminealpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferaseN-AcetylglucosaminyltransferasesUridine Diphosphate N-Acetylglucosamineconvergent evolutionexositeglycosyltranferaseN-glycan processingsubstrate recognition

Identifiers

PMID29666272
PMCPMC5939069
OpenAlexW2800084804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.