Evidence map›Paper›PMID 29666212›Full record

ReviewEssays in biochemistry2018

Extracellular vesicles: important collaborators in cancer progression.

Shinya Sato, Alissa M Weaver

Abstract readReview
In one paragraph

Review in Essays in biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
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  9. Review
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  13. Review
  14. Extracellular vesicles in cancer therapy.Seminars in cancer biology · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Small extracellular vesicles in cancer.Bioactive materials · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shinya SatoDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, USA.
Alissa M WeaverDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, USA alissa.weaver@vanderbilt.edu.
Vanderbilt University · US

Funding

Exosome secretion in breast cancer progressionR01CA206458 · NCI · VANDERBILT UNIVERSITY · PI PONIK, SUZANNE MARIE, WEAVER, ALISSA M · 2016 to 2025
$4.6M
Exosome-Filopodia InteractionsR01GM117916 · NIGMS · VANDERBILT UNIVERSITY · PI WEAVER, ALISSA M · 2016 to 2019
$2.0M
Exocytic pathways in HNSCC progressionR01CA163592 · NCI · VANDERBILT UNIVERSITY · PI WEAVER, ALISSA M · 2012 to 2016
$1.6M
NCI NIH HHS R01 CA163592NCI NIH HHS R01 CA206458NIGMS NIH HHS R01 GM117916
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are membrane vesicles that are released from cells and mediate cell-cell communication. EVs carry protein, lipid, and nucleic acid cargoes that interact with recipient cells to alter their phenotypes. Evidence is accumulating that tumor-derived EVs can play important roles in all steps of cancer progression. Here, we review recent studies reporting critical roles for EVs in four major areas of cancer progression: promotion of cancer invasiveness and motility, enhancement of angiogenesis and vessel permeability, conditioning premetastatic niches, and immune suppression.

Indexed as

Cell CommunicationDisease ProgressionExtracellular VesiclesHumansNeoplasm InvasivenessNeoplasm MetastasisNeoplasmsangiogenesiscancerexosomesmetastasismicrovesiclestumor microenvironments

Identifiers

PMID29666212
PMCPMC6377252
OpenAlexW2802757650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.