SynthesisBMJ open2018
Associations of smoking and alcohol consumption with healthy ageing: a systematic review and meta-analysis of longitudinal studies.
Synthesis in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Determinants and indicators of successful aging as a multidimensional outcome: a systematic review of longitudinal studies.Frontiers in public health · 2023Pooled it
- The Effect of Nutrition on Aging-A Systematic Review Focusing on Aging-Related Biomarkers.Nutrients · 2022Pooled it
- A clinically practical aging clock (physical clock) for healthy aging: development, validation, and application for health assessment and intervention.Science China. Life sciences · 2026Article
- Path analysis of subjective health status, healthy lifestyle habits, and successful aging in Korean older adults: path differences by age.BMC geriatrics · 2026Article
- Modifiable risk factors associated with increased retinal age gap in an Australian population.GeroScience · 2026Article
- The sleep-anxiety dysregulation model of alcohol use disorder risk: A nine-year longitudinal machine learning study.Journal of affective disorders · 2025Review
- But Is Ageing Really All Bad? Conceptualising Positive Ageing.Geriatrics (Basel, Switzerland) · 2025Article
- A new cut-off value of FRAX tools as an osteoporosis screening tool for Thai geriatric population.Scientific reports · 2025Article
- Predictors of high tobacco use prevalence among adults in Autonomous Province of Vojvodina, Serbia.PloS one · 2025Article
- Assessing the Level and Determinants of Active Aging in China: An LDA-Based Topic Modeling Approach.Risk management and healthcare policy · 2025Article
- Prevalence and related factors of healthy aging: A systematic review and meta-analysis.Belitung nursing journal · 2025Review
- Alcohol Consumption Patterns and Mortality Among Older Adults With Health-Related or Socioeconomic Risk Factors.JAMA network open · 2024Article
- Prevalence of smoking among national military service recruits in UAE.Frontiers in public health · 2024Article
- Serum-based biomarkers associated with lung cancer risk and cause-specific mortality in the German randomized Lung Cancer Screening Intervention (LUSI) trial.Translational lung cancer research · 2023Article
- Exploring the association of lifestyle behaviors and healthy ageing among the older adults in India: evidence from LASI survey.BMC geriatrics · 2023Article
- Advanced Activities of Daily Living in Community-Dwelling Older Adults: A Cross-Sectional Study of the Mexican Health and Aging Study (MHAS 2018).Healthcare (Basel, Switzerland) · 2023Article
- Trajectories of alcohol consumption in U.S. military veterans: Results from a 10-year population-based longitudinal study.Drug and alcohol dependence · 2023Article
- Relationship Between Health Literacy and Unhealthy Lifestyle Behaviours in Older Adults Living in Switzerland: Does Social Connectedness Matter?International journal of public health · 2023Article
- Association of Plant Protein Intake with Change in Physical Performance in Chinese Community-Dwelling Older Adults.Nutrients · 2022Article
- An Individually Tailored Program to Increase Healthy Lifestyle Behaviors among the Elderly.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThe number of older people is growing across the world; however, quantitative synthesis of studies examining the impact of lifestyle factors on the ageing process is rare. We conducted a systematic review and meta-analysis of longitudinal studies to synthesise the associations of smoking and alcohol consumption with healthy ageing (HA).
methodsMajor electronic databases were searched from inception to March 2017 (prospectively registered systematic reviews registration number CRD42016038130). Studies were assessed for methodological quality. Random-effect meta-analysis was performed to calculate pooled ORs and 95% CI.
resultsIn total, we identified 28 studies (n=184 543); 27 studies reported results on smoking, 22 on alcohol consumption. 23 studies reported a significant positive association of never or former smoking with HA and 4 non-significant. 12 studies reported a significant positive association of alcohol consumption with HA, 9 no association and 1 negative. Meta-analysis revealed increased pooled OR of HA for never smokers compared with current smokers (2.36, 95% CI 2.03 to 2.75), never smokers compared with former smokers (1.32, 95% CI 1.23 to 1.41), former or never smokers compared with current smokers (1.72, 95% CI 1.20 to 2.47), never smokers compared with past or current smokers (1.29, 95% CI 1.16 to 1.43); drinkers compared with non-drinkers (1.28, 95% CI 1.08 to 1.52), light drinkers compared with non-drinkers (1.12, 95% CI 1.03 to 1.22), moderate drinkers compared with non-drinkers (1.35, 95% CI 0.93 to 1.97) and high drinkers compared with non-drinkers (1.25, 95% CI 1.09 to 1.44). There was considerable heterogeneity in the definition and measurement of HA and alcohol consumption.
conclusionsThere is consistent evidence from longitudinal studies that smoking is negatively associated with HA. The associations of alcohol consumption with HA are equivocal. Future research should focus on the implementation of a single metric of HA, on the use of consistent drinking assessment among studies and on a full-range of confounding adjustment. Our research also highlighted the limited research on ageing in low-and-middle-income countries.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.