Evidence map›Paper›PMID 29665801›Full record

ArticleBiomedical engineering online2018

An extended OpenSim knee model for analysis of strains of connective tissues.

M Marieswaran, Arnab Sikidar, Anu Goel, Deepak Joshi, Dinesh Kalyanasundaram

Open access · goldAbstract read
In one paragraph

Article in Biomedical engineering online, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M MarieswaranCentre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, 110016, India.
Arnab SikidarCentre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, 110016, India.
Anu GoelCentre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, 110016, India.
Deepak JoshiCentre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, 110016, India.
Dinesh KalyanasundaramCentre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, 110016, India. dineshk@cbme.iitd.ac.in.ORCID http://orcid.org/0000-0001-5127-4122
Indian Institute of Technology Delhi · INAll India Institute of Medical Sciences · IN

Funding

Department of Science and Technology India IDP/MED/O5/2014Department of Science and Technology India YSS/2014/000880
6 · The paper itself

Abstract

backgroundOpenSim musculoskeletal models provide an accurate simulation environment that eases limitations of in vivo and in vitro studies. In this work, a biomechanical knee model was formulated with femoral articular cartilages and menisci along with 25 connective tissue bundles representing ligaments and capsules. The strain patterns of the connective tissues in the presence of femoral articular cartilage and menisci in the OpenSim knee model was probed in a first of its kind study.

methodsThe effect of knee flexion (0°-120°), knee rotation (- 40° to 30°) and knee adduction (- 15° to 15°) on the anterior cruciate, posterior cruciate, medial collateral, lateral collateral ligaments and other connective tissues were studied by passive simulation. Further, a new parameter for assessment of strain namely, the differential inter-bundle strain of the connective tissues were analyzed to provide new insights for injury kinematics.

resultsACL, PCL, LCL and PL was observed to follow a parabolic strain pattern during flexion while MCL represented linear strain patterns. All connective tissues showed non-symmetric parabolic strain variation during rotation. During adduction, the strain variation was linear for the knee bundles except for FL, PFL and TL.

conclusionsStrains higher than 0.1 were observed in most of the bundles during lateral rotation followed by abduction, medial rotation and adduction. In the case of flexion, highest strains were observed in aACL and aPCL. A combination of strains at a flexion of 0° with medial rotation of 30° or a flexion of 80° with rotation of 30° are evaluated as rupture-prone kinematics.

Indexed as

Connective TissueModels, BiologicalStress, MechanicalBiomechanical PhenomenaFemaleHumansKnee JointRange of Motion, ArticularDifferential intra-bundle strainLigamentMusculoskeletal modelOpenSimStrain

Identifiers

PMID29665801
PMCPMC5905155
OpenAlexW2804286280

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.