Evidence map›Paper›PMID 29665297›Full record

ArticlePhysiological reports2018

Esmolol acutely alters oxygen supply-demand balance in exercising muscles of healthy humans.

David N Proctor, J Carter Luck, Stephan R Maman, Urs A Leuenberger, Matthew D Muller

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David N ProctorNoll Laboratory, Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania.
J Carter LuckPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Stephan R MamanPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Urs A LeuenbergerPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Matthew D MullerPenn State Heart and Vascular Institute, Penn State University College of Medicine, Hershey, Pennsylvania.
Penn State Milton S. Hershey Medical Center · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Penn State Clinical and Translational Science InstituteKL2TR000126 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$3.2M
NCATS NIH HHS KL2 TR000126NCATS NIH HHS UL1 TR000127
6 · The paper itself

Abstract

Beta-adrenoreceptor antagonists (β blockers) reduce systemic O

Indexed as

Adrenergic beta-1 Receptor AntagonistsAdultAgedBlood PressureExerciseFemaleHealthy VolunteersHeart RateHumansMaleMiddle AgedMuscle, SkeletalOxygen ConsumptionPropanolaminesSpectroscopy, Near-InfraredYoung AdultAdrenergic beta-1 Receptor AntagonistsesmololPropanolaminesBeta-adrenergic blockadeblood pressureheart ratenear-infrared spectroscopyoxygen uptake

Identifiers

PMID29665297
PMCPMC5903697
OpenAlexW2801570035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.