Evidence map›Paper›PMID 29664403›Full record

ArticleCirculation. Heart failure2018

Socioeconomic Disparities in Adherence and Outcomes After Heart Transplant: A UNOS (United Network for Organ Sharing) Registry Analysis.

Brian Wayda, Autumn Clemons, Raymond C Givens, Koji Takeda, Hiroo Takayama, Farhana Latif, Susan Restaino, Yoshifumi Naka, Maryjane A Farr, Paolo C Colombo and 1 more

Abstract read
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Article in Circulation. Heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Unequal Hearts: Racial Disparities Persist in Heart Transplant Outcomes.Journal of the American Heart Association · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Disparities in heart transplant survival and graft rejection outcomes persist in the modern era: a call to race towards a more equitable future.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Heart transplantation in patients from socioeconomically distressed communities.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  17. Review
  18. Increased disparities in waitlist and post-heart transplantation outcomes according to socioeconomic status with the new heart transplant allocation system.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  19. Lung transplantation outcomes in patients from socioeconomically distressed communities.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Brian WaydaFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Autumn ClemonsFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Raymond C GivensFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Koji TakedaFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Hiroo TakayamaFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Farhana LatifFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Susan RestainoFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Yoshifumi NakaFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Maryjane A FarrFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Paolo C ColomboFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY.
Veli K TopkaraFrom the Division of Cardiology, Department of Medicine (B.W., A.C., R.C.G., F.L., S.R., M.A.F., P.C.C., V.K.T.) and Division of Cardiothoracic Surgery, Department of Surgery (K.T., H.T., Y.N.), Columbia University College of Physicians and Surgeons, New York, NY. vt2113@cumc.columbia.edu.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Narrowing the gap between supply and demand in heart transplantationF32HL154750 · NHLBI · STANFORD UNIVERSITY · PI WAYDA, BRIAN · 2022 to 2024
$165k
NCATS NIH HHS UL1 TR001873NHLBI NIH HHS F32 HL154750
6 · The paper itself

Abstract

backgroundThere is mixed evidence of racial and socioeconomic disparities in heart transplant outcomes. Their underlying cause-and whether individual- or community-level traits are most influential-remains unclear. The current study aimed to characterize socioeconomic disparities in outcomes and identify time trends and mediators of these disparities. METHODS AND

resultsWe used United Network for Organ Sharing registry data and included 33 893 adult heart transplant recipients between 1994 and 2014. Socioeconomic status (SES) indicators included insurance, education, and neighborhood SES measured using a composite index. Black race and multiple indicators of low SES were associated with the primary outcome of death or retransplant, independent of baseline clinical characteristics. Blacks had lower HLA and race matching, but further adjustment for these and other graft characteristics only slightly attenuated the association with black race (HR, 1.25 after adjustment). This and the associations with neighborhood SES (HR, 1.19 for lowest versus highest decile), Medicare (HR, 1.17), Medicaid (HR, 1.29), and college education (HR, 0.90) remained significant after full adjustment. When comparing early (1994-2000) and late (2001-2014) cohorts, the disparities associated with the middle (second and third) quartiles significantly decreased over time, but those associated with lowest SES quartile and black race persisted. Low neighborhood SES was also associated with higher risks of noncompliance (HR, 1.76), rejection (HR, 1.28), hospitalization (HR, 1.13), and infection (HR, 1.10).

conclusionsRacial and socioeconomic disparities exist in heart transplant outcomes, but the latter may be narrowing over time. These disparities are not explained by differences in clinical or graft characteristics.

Indexed as

Heart TransplantationRacial GroupsSocioeconomic FactorsAdultAgedEthnicityFemaleHealthcare DisparitiesHeart FailureHumansMaleMedicaidMedicareMiddle AgedRegistriesSocial Classdeathheart failurehospitalizationMedicaidtransplantation

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.