ArticleEmerging infectious diseases2018
Dynamics of Spirochetemia and Early PCR Detection of Borrelia miyamotoi.
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Tick borne relapsing fever - a systematic review and analysis of the literature.PLoS neglected tropical diseases · 2022Pooled it
- Laboratory Methods for Detection of Infectious Agents and Serological Response in Humans With Tick-Borne Infections: A Systematic Review of Evaluations Based on Clinical Patient Samples.Frontiers in public health · 2021Pooled it
- Article
- Variety of Bacterial Pathogens in Ticks Removed from Humans, Northeastern China.Microorganisms · 2025Article
- Incidence of Lyme borreliosis following Ixodes ricinus tick bites in Poland: a citizen science approach.Parasites & vectors · 2025Article
- Analytical comparison of 11 CE-IVD marked real-time PCR assays for Borrelia burgdorferi sensu lato detection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Tick-borne Disease with Yezo Virus and Borrelia miyamotoi Coinfection.Internal medicine (Tokyo, Japan) · 2024Article
- HumanPathogens (Basel, Switzerland) · 2023Review
- Review
- Development and Validation of a Protein Array for Detection of Antibodies against the Tick-Borne Pathogen Borrelia miyamotoi.Microbiology spectrum · 2022Article
- Babesiosis in Southeastern, Central and Northeastern Europe: An Emerging and Re-Emerging Tick-Borne Disease of Humans and Animals.Microorganisms · 2022Review
- No molecular detection of tick-borne pathogens in the blood of patients with erythema migrans in Belgium.Parasites & vectors · 2022Article
- Simultaneous Detection and Differentiation of Clinically Relevant Relapsing FeverJournal of clinical microbiology · 2021Article
- Review
- Pathogenesis of Relapsing Fever.Current issues in molecular biology · 2021Review
- Presence of Borrelia miyamotoi infection in a highly endemic area of Lyme disease.Annals of clinical microbiology and antimicrobials · 2020Article
- Assessment of Borrelia miyamotoi in febrile patients and ticks in Alsace, an endemic area for Lyme borreliosis in France.Parasites & vectors · 2020Article
- Lyme Disease: Diversity ofHealthcare (Basel, Switzerland) · 2020Article
- Emerging Tick-Borne Diseases.Clinical microbiology reviews · 2020Review
- Commentary:Frontiers in medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated whether Borrelia miyamotoi disease can be detected in its early stage by using PCR for borrelial 16S rRNA, which molecule (DNA or RNA) is the best choice for this test, and whether spirochetes are present in blood during the acute phase of B. miyamotoi disease. A total of 473 patients with a suspected tickborne infection in Yekaterinburg, Russia, in 2009, 2010, and 2015 were enrolled in this study. Blood samples were analyzed by using quantitative PCR or ELISA, and a diagnosis of borreliosis was confirmed for 310 patients. For patients with erythema migrans, 5 (3%) of 167 were positive for B. miyamotoi by PCR; for patients without erythema migrans, 65 (45%) of 143 were positive for B. miyamotoi by PCR. The median concentration for RNA was 3.8 times that for DNA. Median time for detection of B. miyamotoi in blood was 4 days.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.