Evidence map›Paper›PMID 29664169›Full record

ArticleTransfusion2018

Improving quality of care for patients with iron deficiency anemia presenting to the emergency department.

Fatima Khadadah, Jeannie Callum, Dominick Shelton, Yulia Lin

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Transfusion, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05304442 (Intravenous Ferric Derisomaltose for Moderate to Severe Anemia Due to Uterine Bleeding in the Emergency Department), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05304442 phase3recruitingnot on this mapstarted 2022, after this paper: background citation

Intravenous Ferric Derisomaltose for Moderate to Severe Anemia Due to Uterine Bleeding in the Emergency Department: a Randomized Trial

TypeinterventionalSponsorBaylor College of MedicineRan2022 to 2025Enrolled40ConditionsAnemia, Iron Deficiency, Uterine BleedingArmsFerric Derisomaltose 1000 Mg in 10 mL INTRAVENOUS SOLUTION [Monoferric], Ferrous Sulfate 65 mg elemental iron (325 mg tablets)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  8. Choosing Wisely® in Hematology: Have We Made a Difference?Current hematologic malignancy reports · 2020
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Fatima KhadadahFaculty of Medicine, University of Toronto, Toronto, Canada.
Jeannie CallumDepartment of Laboratory Medicine & Molecular Diagnostics, Sunnybrook Health Sciences Centre, and Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Canada.
Dominick SheltonDepartment of Emergency Medicine, Sunnybrook Health Sciences Centre, and University of Toronto, Toronto, Canada.
Yulia LinDepartment of Laboratory Medicine & Molecular Diagnostics, Sunnybrook Health Sciences Centre, and Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Canada.
University of Toronto · CAHealth Sciences Centre · CASunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients presenting to the emergency department (ED) with iron deficiency anemia (IDA) are underrecognized, undertreated with iron, and overtransfused. A 3-month audit of red blood cell (RBC) transfusions at the Sunnybrook Health Sciences Centre ED in 2013 showed that only 53% of transfusions for IDA were appropriate. The aim of this quality improvement project was to increase the rate of appropriate transfusion to greater than 80%. STUDY DESIGN AND

methodsSince November 2013, several quality improvement interventions have been implemented, including educational presentations, development of an algorithm on IDA management in the ED, and development of an ED IDA toolkit. The primary outcome was appropriateness of RBC transfusions per month. The process measure was monthly intravenous (IV) iron use in IDA patients managed exclusively by ED staff. Balancing measures included IV iron use according to the algorithm and undertransfusion.

resultsOver a 24-month period beginning January 2014, assessment of 193 units transfused in the ED showed an improvement of RBC appropriateness to 91% (range 50%-100%). IV iron use increased from one dose in the 3-month audit to an average of 2.6 and 4.7 per month in 2014 and 2015, respectively. IV iron use did not follow the algorithm in 19% (18 of 93) of cases: 12 were given to patients with less severe iron deficiency or bleeding.

conclusionImproved RBC transfusion appropriateness for IDA in the ED can be achieved and maintained with the implementation of simple educational and practical interventions.

Indexed as

Quality ImprovementQuality of Health CareAlgorithmsAnemia, Iron-DeficiencyEmergency Service, HospitalErythrocyte TransfusionHumansIronIron

Identifiers

PMID29664169
OpenAlexW2800421343

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.