Evidence map›Paper›PMID 29663443›Full record

ArticleClinical cardiology2018

Time trends in antithrombotic management of patients with atrial fibrillation treated with coronary stents: Results from TALENT-AF (The internAtionaL stENT - Atrial Fibrillation study) multicenter registry.

Brian J Potter, Giuseppe Andò, Giovanni Cimmino, Ricardo Ladeiras-Lopes, Zied Frikah, Xin Yue Chen, Vittorio Virga, Joao Goncalves-Almeida, A John Camm, Keith A A Fox

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Brian J PotterCHUM Research Center and Cardiovascular Center, Montréal, Canada.
Giuseppe AndòDepartment of Clinical and Experimental Medicine, Section of Cardiology, University Hospital of Messina, Messina, Italy.ORCID http://orcid.org/0000-0001-5552-6382
Giovanni CimminoDepartment of Cardiothoracic and Respiratory Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Ricardo Ladeiras-LopesDepartment of Cardiology, Gaia Hospital Centre, Vila Nova de Gaia, Portugal.
Zied FrikahCHUM Research Center and Cardiovascular Center, Montréal, Canada.
Xin Yue ChenCHUM Research Center and Cardiovascular Center, Montréal, Canada.
Vittorio VirgaDepartment of Clinical and Experimental Medicine, Section of Cardiology, University Hospital of Messina, Messina, Italy.
Joao Goncalves-AlmeidaDepartment of Cardiology, Gaia Hospital Centre, Vila Nova de Gaia, Portugal.
A John CammSt. George's University of London, London, United Kingdom.
Keith A A FoxCentre for Cardiovascular Science and Royal Infirmary, Edinburgh, United Kingdom.
Centro Hospitalar de Vila Nova de Gaia · PTUniversity of Messina · ITEdinburgh Royal Infirmary · GBSt George's, University of London · GBUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntithrombotic management of patients with atrial fibrillation (AF) requiring percutaneous coronary intervention (PCI) is highly variable; limited evidence-based guidelines exist to influence practice. HYPOTHESIS: Patient characteristics and availability of novel drugs may have contributed to practice variability.

methodsWe undertook an international multicenter retrospective registry of AF patients treated with PCI. The primary measures of interest were antiplatelet and OAC prescriptions at discharge. We compared temporal trends between Prior (2010-2012) and Recent (2013-2015) cohorts and investigated variables associated with OAC prescription.

resultsWe identified 488 cases (140 Prior, 348 Recent). Median CHADS

conclusionsDespite little change over time in clinical characteristics of AF patients undergoing PCI, significantly more patients received OAC at presentation. However, triple therapy was not more frequent in the Recent cohort, and ACS presentation was associated with lack of OAC at discharge. We underscore the need for trial evidence and use of updated guidelines to assist clinicians in balancing ischemic and bleeding risks.

Indexed as

StentsAdministration, OralAgedAged, 80 and overAnticoagulantsAtrial FibrillationCanadaChi-Square DistributionCoronary DiseaseDrug PrescriptionsFemaleFibrinolytic AgentsHemorrhageHumansItalyMaleAnticoagulantsFibrinolytic AgentsPlatelet Aggregation InhibitorsAtrial FibrillationDrug-Eluting StentsGuidelinesOral Anticoagulants

Identifiers

PMID29663443
PMCPMC6490076
OpenAlexW2802804417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.