ArticleEnvironmental science and pollution research international2018
Development of QSAR model for predicting the inclusion constants of organic chemicals with α-cyclodextrin.
Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- A Review of Machine Learning and QSAR/QSPR Predictions for Complexes of Organic Molecules with Cyclodextrins.Molecules (Basel, Switzerland) · 2024Review
- Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin:Journal of enzyme inhibition and medicinal chemistry · 2021Article
- Computer-Aided Discovery of New Solubility-Enhancing Drug Delivery System.Biomolecules · 2020Article
- Development of quantitative structure-property relationship model for predicting the field sampling rate (REnvironmental science and pollution research international · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solubility is a crucial limiting factor in pharmaceutical research and contaminated site remediation. Cyclodextrin, with its structure of hydrophilic exterior and hydrophobic cavity, has a potential ability to enhance the hydrophobic chemical's solubility through the formation of host-guest complex. The stability of host-guest complex is often quantified by the inclusion constant. In this study, the logarithm of 1:1 α-cyclodextrin inclusion constants (log K
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