Evidence map›Paper›PMID 29663178›Full record

ArticleThe international journal of cardiovascular imaging2018

Validation of contrast-enhanced time-resolved magnetic resonance angiography in pre-ablation planning in patients with atrial fibrillation: comparison with traditional technique.

Tarek Zghaib, Adeel Shahid, Chiara Pozzessere, Kristin K Porter, Linda C Chu, John Eng, Hugh Calkins, Ihab R Kamel, Saman Nazarian, Stefan L Zimmerman

Abstract readComparative StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Cardiovascular imaging 2018 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tarek ZghaibDivision of Cardiology, Johns Hopkins Medicine, 600 N Wolfe St, Carnegie 592, Baltimore, MD, 21287, USA. tarek.z@jhmi.edu.ORCID http://orcid.org/0000-0003-4814-6319
Adeel Shahid§Russell A. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medicine, Baltimore, MD, USA.
Chiara Pozzessere§Russell A. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medicine, Baltimore, MD, USA.
Kristin K PorterDepartment of Radiology, University of Alabama at Birmingham, Birmingham, USA.
Linda C Chu§Russell A. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medicine, Baltimore, MD, USA.
John Eng§Russell A. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medicine, Baltimore, MD, USA.
Hugh CalkinsDivision of Cardiology, Johns Hopkins Medicine, 600 N Wolfe St, Carnegie 592, Baltimore, MD, 21287, USA.
Ihab R Kamel§Russell A. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medicine, Baltimore, MD, USA.
Saman NazarianDivision of Cardiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Stefan L Zimmerman§Russell A. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medicine, Baltimore, MD, USA.
Johns Hopkins University · USUniversity of Alabama at Birmingham · USUniversity of Pennsylvania · US

Funding

ANCILLARY STUDY OF SUBSTRATE AND INTERVENTION MECHANISMS FOR MALIGNANT ARRHYTHMIAR01HL116280 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI NAZARIAN, SAMAN · 2013 to 2016
$1.2M
Applications of Magnetic Resonance for Management of Ventricular TachycardiaK23HL089333 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI NAZARIAN, SAMAN · 2010 to 2014
$686k
National Institutes of Health K23HL089333National Institutes of Health R01HL116280NHLBI NIH HHS K23 HL089333NHLBI NIH HHS R01 HL116280
6 · The paper itself

Abstract

Bolus timing is critical to optimal magnetic resonance angiography (MRA) acquisitions but can be challenging in some patients. Our purpose was to evaluate whether contrast-enhanced time-resolved magnetic resonance angiography (TR-MRA), a dynamic multiphase sequence that does not rely on bolus timing, is a viable alternative method to conventional 3D fast-long angle shot contrast-enhanced magnetic resonance angiography (CE-MRA). Coronal subtracted conventional CE-MRA images in 50 consecutive patients presenting for pre-atrial fibrillation ablation pulmonary venous (PV) mapping were compared with 50 TR-MRA images performed in 50 subsequent patients. The TR-MRA protocol was modified to optimize spatial resolution with slightly reduced temporal resolution (6.1 s scan time). Three experienced readers evaluated each scan's image quality and relative left atrial (LA) opacification based on a 4-point scale and diagnostic PV visualization in a binary fashion. Additionally, LA signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and PV dimensions were measured for both techniques. TR-MRA had significantly higher overall image quality (3.10 ± 0.69 vs. 2.42 ± 0.69, p < 0.0001), and LA opacification scores (3.33 ± 0.70 vs. 2.15 ± 1.13, p < 0.0001) compared to CE-MRA. The proportion of diagnostically visualized pulmonary veins was 137/150 (91%) in the CE-MRA group vs. 147/150 (98%) with TR-MRA (p = 0.010). Both SNR and CNR were higher with TR-MRA vs. CE-MRA (277.9 ± 48.9 vs. 106.8 ± 41, p = 0.002 and 100.3 ± 41.7 vs. 70.7 ± 48.0, p = 0.002, respectively). Inter-reader variance of individual PV measurements for each of the MR techniques ranged between 0.62 and 1.47 mm and the ICC for vein measurements was higher with TR-MRA (range: 0.62-0.81) compared to CE-MRA (range: 0.47-0.64). TR-MRA, modified to maximize spatial resolution, offers an alternative method for performing high quality MRA examinations in patients with AF. TR-MRA offers greater overall image quality, PV visualization, and similarly reproducible PV measurements compared to traditional CE-MRA, without the challenges of proper bolus timing.

Indexed as

Catheter AblationMagnetic Resonance AngiographyAdultAgedAged, 80 and overAtrial FibrillationFemaleHeart AtriaHumansImaging, Three-DimensionalMaleMiddle AgedPredictive Value of TestsPulmonary VeinsRetrospective StudiesAtrial fibrillationCatheter ablationContrast-enhanced magnetic resonance angiographyTime-resolved magnetic resonance angiography

Identifiers

PMID29663178
PMCPMC6093807
OpenAlexW2800912458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.