ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2018
Vertebral body osteonecrosis: proposal of a treatment-oriented classification system.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Osteonecrosis in Youth with Sickle Cell Disease-A Narrative Review.Children (Basel, Switzerland) · 2026Review
- The Elusive Concept of Stability in Osteoporotic Vertebral Fractures: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Case review of 3 patients with musculoskeletal manifestation of human immunodeficiency virus and highly active antiretroviral therapy in the form of osteopenia and insufficiency fractures.BJR case reports · 2026Review
- The surgical strategy selection and clinical efficacy analysis of Kummell's disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Osteoporotic vertebral fractures localized in the lumbar area significantly impact sagittal alignment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- Simplified Pedicle Subtraction Osteotomy for Osteoporotic Vertebral Fractures.International journal of spine surgery · 2021Article
- Novel Surgical Strategy for Treating Osteoporotic Vertebral Fractures with Cord Compression.Orthopaedic surgery · 2019Article
- Analysis of percutaneous kyphoplasty or short-segmental fixation combined with vertebroplasty in the treatment of Kummell disease.Journal of orthopaedic surgery and research · 2019Review
- What is the Current Evidence on Vertebral Body Osteonecrosis?: A Systematic Review of the Literature.Asian spine journal · 2018Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo present a classification system for vertebral body osteonecrosis (VBON) based on imaging findings and sagittal alignment and consequently to propose treatment guidelines.
methodsChart review and classification of imaging and clinical findings. An analysis of literature about VBON has been evaluated to conceive the classification. The current data allows to correlate radiological findings with different stages of the pathophysiological process and consequently to propose a patient-tailored treatment plan.
resultsThe classification identifies 4 stages: stage 0 (theoretical phase), stage 1 (early phase), stage 2 (instability phase) and stage 3 (fixed deformity phase). Local (angular kyphosis expressed as anterior-posterior wall height ratio) and global (sagittal vertical axis and pelvic tilt) sagittal alignment are considered as complementary modifiers to tailor the most suitable treatment. Stage 1 is generally managed conservatively. Stage 2 and 3 often require different surgical approaches according to local and global sagittal alignment.
conclusionsThe classification allows a systematic staging of this disease and can help establish a proper and patient-oriented treatment plan. Further researches are advocated to fully validate the proposed classification system. These slides can be retrieved under Electronic Supplementary Material.
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