ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018
Health-related quality of life among cancer patients in their last year of life: results from the PROFILES registry.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Survivorship care for people affected by advanced or metastatic cancer: MASCC-ASCO standards and practice recommendations.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Protein intake, weight loss, dietary intervention, and worsening of quality of life in older patients during chemotherapy for cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Latent transition analysis of end-of-life care trajectories among cancer patients in South Korea: a nationwide cohort study.BMC health services research · 2026Article
- Observational
- Initial quality of life and influencing factors in patients with advanced cancer receiving home hospice care: A propensity score-matched analysis stratified by survival period.Asia-Pacific journal of oncology nursing · 2025Article
- Health-related quality of life in patients with advanced soft tissue sarcoma receiving first-line palliative chemotherapy (HOLISTIC): longitudinal results from a prospective, observational cohort study.EClinicalMedicine · 2025Article
- Health Outcomes and Symptom Intensity Over Time among Cancer Patients Receiving Palliative Care in Vietnam: A Prospective Cohort Study.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Trajectory of quality of life among patients with cancer at the end of life: a longitudinal survey study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Dyadic effects of perceived burden and psychological distress on quality of life among Chinese advanced cancer patients and their caregivers.Scientific reports · 2025Article
- Socioeconomic disparities in health-related quality of life and healthcare use in the last year of life of patients with advanced cancer: longitudinal results from the eQuiPe study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Longitudinal health-related quality of life in patients with pancreatic cancer stratified by treatment: a nationwide cohort study.EClinicalMedicine · 2025Article
- Patient-Reported Outcome Measures in Patients with and without Non-Expandable Lung Secondary to Malignant Pleural Effusion-A Single-Centre Observational Study.Diagnostics (Basel, Switzerland) · 2024Article
- Characteristics of timely integration of palliative care into oncology hospital care for patients with incurable cancer: results of a Delphi Study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Article
- Quantifying bias due to missing data in quality of life surveys of advanced-stage cancer patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Quality of care and quality of life as experienced by patients with advanced cancer of a rare tumour type: results of the multicentre observational eQuiPe study.Journal of cancer survivorship : research and practice · 2023Observational
- Perception of prognosis and health-related quality of life in patients with advanced cancer: results of a multicentre observational study (eQuiPe).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Observational
- The role of cancer nurses in cancer-related pain management in Europe.Palliative care and social practice · 2023Review
- Trajectory of health-related quality of life during the last year of life in patients with advanced non-small-cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Trajectories of Health-related quality of life in patients with Advanced Cancer during the Last Year of Life: findings from the COMPASS study.BMC palliative care · 2022Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeThe aim of this study was to assess health-related quality of life (HRQoL) in the last year of life of cancer patients stratified by four periods of time before death. PATIENTS AND
methodsBetween 2008 and 2015, cancer patients were invited to participate in PROFILES (Patient Reported Outcomes Following Initial Treatment and Long-term Evaluation of Survivorship) registry studies. Patients were eligible for inclusion in this secondary analysis if they had been invited to complete the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) in their last year of life (N = 892). Four hundred fifty-eight patients (51%) responded. Descriptive statistics were used to describe the HRQoL of cancer patients in the last 3 months of life (N = 61), the last 3-6 months (N = 110), the last 6-9 months (N = 138), or the last 9-12 months of their life (N = 129).
resultsPatients in the last 3 months report a significant lower HRQoL, lower functioning, and higher symptom burden of fatigue and appetite loss compared to patients in different time periods before death (p < 0.008). Clinical relevance of the differences for global QoL, cognitive, and social functioning was large. Patients' HRQoL in the last year of life was significantly lower than that of the normative population (p < 0.001).
conclusionsAll aspects of HRQoL are considerably impaired in patients with advanced cancer, with a marked lower HRQoL in the final months of life. This marked decline of HRQoL in the final months of life may be an indicator of approaching death and serve as an important trigger for end-of-life communication and decision-making about subsequent treatment and supportive care.
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