ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2018
Urea and plasma ice-nucleating proteins promoted the modest freeze tolerance in Pleske's high altitude frog Nanorana pleskei.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 19 citations in OpenAlex.
- Comparative transcriptomic analysis delineates adaptation strategies of Rana kukunoris toward cold stress on the Qinghai-Tibet Plateau.BMC genomics · 2024Article
- Integrative proteome and metabolome analyses reveal molecular basis of the tail resorption during the metamorphic climax ofFrontiers in cell and developmental biology · 2024Article
- Multi-omics Investigation of Freeze Tolerance in the Amur Sleeper, an Aquatic Ectothermic Vertebrate.Molecular biology and evolution · 2023Article
- Seasonal variations in the intermediate metabolism in South American tree-frog Boana pulchella.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Article
- Freeze tolerance and the underlying metabolite responses in the Xizang plateau frog, Nanorana parkeri.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021Article
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7 authors at 2 institutions in 1 country.
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Abstract
The frog Nanorana pleskei (Dicroglossidae) is indigenous to the Qinghai-Tibetan Plateau. To identify its strategies in coping with the cold climate, we measured the hibernacula microhabitat temperature during winter. We also examined the freezing-induced and seasonal variation of several putative cryoprotectants in the heart, liver, brain, kidney and muscle, as well as ice-nucleating protein in plasma. Our results showed that N. pleskei survived exposure to temperatures as low as - 2.5 ± 0.40 °C during hibernation, which was lower than the body fluid freezing point (- 0.43 ± 0.01 °C). Experimental freezing results indicated that four of six specimens could survive 12 h of freezing at - 2 °C with 27.5 ± 2.5% of total body water as ice. Concomitantly, the water contents of all examined organs decreased after being frozen for 24 h at - 2 °C. The levels of urea in heart significantly increased from 71.05 ± 7.19 to 104.59 ± 10.11 µmol g
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