Evidence map›Paper›PMID 29663027›Full record

ReviewSeminars in immunopathology2018

Molecular interactions at the surface of extracellular vesicles.

Edit I Buzás, Eszter Á Tóth, Barbara W Sódar, Katalin É Szabó-Taylor

Abstract readReview
In one paragraph

Review in Seminars in immunopathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 227 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
227citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

227 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Investigating Dietary microRNA Stability and Function Using a Transgenic Milk Model With Unique microRNA Sequences.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  4. Article
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  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Comparison of Methods for the Isolation of Salivary Extracellular Vesicles.International journal of molecular sciences · 2026
    Article
  13. Review
  14. Article
  15. Rethinking Extracellular Vesicle Signaling.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

167 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edit I BuzásDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary. buzas.edit@med.semmelweis-univ.hu.ORCID http://orcid.org/0000-0002-3744-206X
Eszter Á TóthDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.
Barbara W SódarDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.
Katalin É Szabó-TaylorDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.

Funding

Ministry for National Economy of Hungary VEKOP-2.3.2-16-2016-00002 and VEKOP-2.3.3-15-2016-00016National Research, Development and Innovation Office NKFIH, Hungary OTKA11958, OTKA120237, NVKP_16-1-2016-0017
6 · The paper itself

Abstract

Extracellular vesicles such as exosomes, microvesicles, apoptotic bodies, and large oncosomes have been shown to participate in a wide variety of biological processes and are currently under intense investigation in many different fields of biomedicine. One of the key features of extracellular vesicles is that they have relatively large surface compared to their volume. Some extracellular vesicle surface molecules are shared with those of the plasma membrane of the releasing cell, while other molecules are characteristic for extracellular vesicular surfaces. Besides proteins, lipids, glycans, and nucleic acids are also players of extracellular vesicle surface interactions. Being secreted and present in high number in biological samples, collectively extracellular vesicles represent a uniquely large interactive surface area which can establish contacts both with cells and with molecules in the extracellular microenvironment. Here, we provide a brief overview of known components of the extracellular vesicle surface interactome and highlight some already established roles of the extracellular vesicle surface interactions in different biological processes in health and disease.

Indexed as

AnimalsCell CommunicationCell MembraneCellular MicroenvironmentExtracellular VesiclesHumansDrug deliveryExtracellular matrixExtracellular vesicleInteractomeSurface

Identifiers

PMID29663027
PMCPMC6208672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.