ArticleBlood research2018
Splenic myeloid metaplasia in warm autoimmune hemolytic anemia (wAIHA): a retrospective study.
Article in Blood research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Treatment and clinical outcomes of pediatric autoimmune hemolytic anemia: real-world single-center data from Korea.Clinical and experimental pediatrics · 2025Article
- A New Murine Model of Primary Autoimmune Hemolytic Anemia (AIHA).Frontiers in immunology · 2021Article
- Treatment of autoimmune hemolytic anemia: real world data from a reference center in Mexico.Blood research · 2019Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSplenic myeloid metaplasia (SMM) is a kind of extramedullary hematopoiesis, whereas its clinical significance in wAIHA remains unclear. The aim of this study is evaluating the frequency and clinical characteristics of SMM, compared with splenic-congestion (SC).
methodsWe included patients with wAIHA treated in a Mexican tertiary hospital between January 1992 and December 2015. All patients received steroids as first-line treatment and splenectomy as second-line treatment.
resultsAmong the thirty-six splenectomized patients, 15 (41.6%) and 21 (58.4%) were diagnosed as SMM and SC, respectively. No differences were found in clinical characteristics between two groups. SMM patients showed lower platelet count (147×10
conclusionThe wAIHA patients with SMM have different biological profiles with those without SMM. This study is the first trial evaluating the significance of histopathological spleen findings and their association with rheumatologic profile.
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