ArticleFrontiers in cellular and infection microbiology2018
The CpxA/CpxR Two-Component System Affects Biofilm Formation and Virulence in
Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 60 citations in OpenAlex.
- Overview of functionally characterized two-component regulatory systems in Vibrio parahaemolyticus.Archives of microbiology · 2026Review
- The CpxR response regulator mediates the virulence ofMicrobiology spectrum · 2026Article
- Comprehensive Study of Antibiotic Resistance inAntibiotics (Basel, Switzerland) · 2024Article
- Comprehensive Assessment of Multidrug-Resistant and Extraintestinal PathogenicMicroorganisms · 2024Article
- The morphology and metabolic changes of Actinobacillus pleuropneumoniae during its growth as a biofilm.Veterinary research · 2023Article
- Bacterial virulence regulation through soluble peptidoglycan fragments sensing and response: knowledge gaps and therapeutic potential.FEMS microbiology reviews · 2023Article
- The Two-Component System CpxRA Affects Antibiotic Susceptibility and Biofilm Formation in Avian PathogenicAnimals : an open access journal from MDPI · 2023Article
- Effects of OxyR regulator on oxidative stress, Apx toxin secretion and virulence ofFrontiers in cellular and infection microbiology · 2023Article
- The two-component system CpxAR is required for the high potassium stress survival ofFrontiers in microbiology · 2023Article
- Systematic Identification of CpxRA-Regulated Genes and Their Roles in Escherichia coli Stress Response.mSystems · 2022Article
- Cpx-signalling facilitates Hms-dependent biofilm formation by Yersinia pseudotuberculosis.NPJ biofilms and microbiomes · 2022Article
- The two-component system CpxA/CpxR is critical for full virulence inFrontiers in microbiology · 2022Article
- Involvement of theFrontiers in veterinary science · 2022Article
- The CpxA/CpxR two-component system mediates regulation ofFrontiers in microbiology · 2022Article
- The DegU Orphan Response Regulator Contributes to Heat Stress Resistance inFrontiers in cellular and infection microbiology · 2021Article
- Characterization of the TyrR Regulon in the Rhizobacterium Enterobacter ludwigii UW5 Reveals Overlap with the CpxR Envelope Stress Response.Journal of bacteriology · 2020Article
- A CpxR-RegulatedInfection and immunity · 2020Article
- The CpxAR Two-Component System Contributes to Growth, Stress Resistance, and Virulence ofFrontiers in microbiology · 2020Article
- The Yersinia pseudotuberculosis Cpx envelope stress system contributes to transcriptional activation of rovM.Virulence · 2019Article
- Role of CpxR in Biofilm Development: Expression of Key Fimbrial, O-Antigen and Virulence Operons ofInternational journal of molecular sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gram-negative bacteria have evolved numerous two-component systems (TCSs) to cope with external environmental changes. The CpxA/CpxR TCS consisting of the kinase CpxA and the regulator CpxR, is known to be involved in the biofilm formation and virulence of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.