ArticleClinical and experimental reproductive medicine2018
Sperm chromatin and DNA integrity, methyltransferase mRNA levels, and global DNA methylation in oligoasthenoteratozoospermia.
Article in Clinical and experimental reproductive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- The role of spermatozoa-zona pellucida interaction in selecting fertilization-competent spermatozoa in humans.Frontiers in endocrinology · 2023Article
- Prepubertal nutritional modulation in the bull and its impact on sperm DNA methylation.Cell and tissue research · 2022Article
- Relationship between sperm quality and total fertilization failure in intracytoplasmic sperm injection and in vitro fertilization cycles: A cross-sectional study.International journal of reproductive biomedicine · 2022Article
- Unraveling the Molecular Impact of Sperm DNA Damage on Human Reproduction.Advances in experimental medicine and biology · 2022Article
- Coding and Non-Coding RNAs, as Male Fertility and Infertility Biomarkers.International journal of fertility & sterility · 2021Review
- Protective effects of curcumin on chromatin quality, sperm parameters, and apoptosis following testicular torsion-detorsion in mice.Clinical and experimental reproductive medicine · 2021Article
- Global Methylation and Protamine Deficiency in Ram Spermatozoa Correlate with Sperm Production and Quality but Are Not Influenced by Melatonin or Season.Animals : an open access journal from MDPI · 2020Article
- Critical Review on the Presence of Phthalates in Food and Evidence of Their Biological Impact.International journal of environmental research and public health · 2020Review
- Discovery of the Involvement in DNA Oxidative Damage of Human Sperm Nuclear Basic Proteins of Healthy Young Men Living in Polluted Areas.International journal of molecular sciences · 2020Article
- The effect of vitamin C on the gene expression profile of sperm protamines in the male partners of couples with recurrent pregnancy loss: A randomized clinical trial.Clinical and experimental reproductive medicine · 2020Article
- Influence of Lifestyle and Environmental Factors on Semen Quality in Ghanaian Men.International journal of reproductive medicine · 2020Article
- CircRNA Role and circRNA-Dependent Network (ceRNET) in Asthenozoospermia.Frontiers in endocrinology · 2020Article
- Epigenetics of Male Fertility: Effects on Assisted Reproductive Techniques.The world journal of men's health · 2019Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate sperm chromatin/DNA integrity, global DNA methylation, and
methodsSemen samples from 32 OAT patients who comprised the case group and 32 normozoospermic men who comprised the control group were isolated and purified using a standard gradient isolation procedure according to World Health Organization criteria.
resultsSignificantly higher proportions of AB+, TB+, CMA3+, and TUNEL+ spermatozoa, as well as
conclusionOligoasthenoteratozoospermic men showed abnormal sperm parameters, abnormal chromatin/DNA integrity, and a higher global DNA methylation rate, as well as overexpression of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.