ArticleJournal of orthopaedic translation2018
Quantitative analysis of T2 relaxation times of the patellofemoral joint cartilage 3 years after anterior cruciate ligament reconstruction.
Article in Journal of orthopaedic translation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Molecular cartilage pathology following anterior cruciate ligament reconstruction: a systematic review of MRI studies.Frontiers in surgery · 2026Pooled it
- Are Altered Knee Joint Biomechanics Associated with Future Post-Traumatic Osteoarthritis Outcomes? A Systematic Review and Meta-Analysis of Longitudinal Studies.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- MRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2019Pooled it
- Short-Term Contact Kinematic Changes and Longer-Term Biochemical Changes in the Cartilage After ACL Reconstruction: A Pilot Study.Annals of biomedical engineering · 2018Trial
- Increased joint line obliquity is associated with lateral cartilage degeneration after medial opening wedge high tibial osteotomy: a quantitative MRI analysis.Knee surgery & related research · 2026Article
- Persistent underloading of patellofemoral joint following hamstring autograft ACL reconstruction is associated with cartilage health.Osteoarthritis and cartilage · 2023Article
- Patellofemoral contact forces and knee gait mechanics 3 months after ACL reconstruction are associated with cartilage degradation 24 months after surgery.Osteoarthritis and cartilage · 2023Article
- Multi-vendor multi-site quantitative MRI analysis of cartilage degeneration 10 Years after anterior cruciate ligament reconstruction: MOON-MRI protocol and preliminary results.Osteoarthritis and cartilage · 2022Article
- Factors Influencing the Progression of Patellofemoral Articular Cartilage Damage After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2022Article
- Hip-Knee Joint Coordination Patterns are Associated With Patellofemoral Joint Cartilage Composition in Patients With Anterior Cruciate Ligament Reconstruction.Journal of applied biomechanics · 2022Article
- Pre-Operative Femoral Cartilage Ultrasound Characteristics Are Altered in People Who Report Symptoms at 1 year After Anterior Cruciate Ligament Reconstruction.Ultrasound in medicine & biology · 2021Article
- Patient-Reported Outcomes and Knee Mechanics Correlate With Patellofemoral Deep Cartilage UTE-T2* 2 Years After Anterior Cruciate Ligament Reconstruction.The American journal of sports medicine · 2021Article
- Femoral Cartilage Ultrasound Echo Intensity Associates with Arthroscopic Cartilage Damage.Ultrasound in medicine & biology · 2021Article
- Correlation of T2* relaxation times of the retropatellar cartilage with tibial tuberosity-trochlea groove distance in professional soccer players.Scientific reports · 2020Article
- Alterations in articular cartilage T2 star relaxation time following mechanical disorders: in vivo canine supraspinatus tendon resection models.BMC musculoskeletal disorders · 2020Article
- Prevalence of patellofemoral joint osteoarthritis after anterior cruciate ligament injury and associated risk factors: A systematic review.Journal of orthopaedic translation · 2020Review
- Slower Walking Speed Is Related to Early Femoral Trochlear Cartilage Degradation After ACL Reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Osteoarthritis year in review 2018: mechanics.Osteoarthritis and cartilage · 2019Review
- Clinical translation and application in orthopaedics.Journal of orthopaedic translation · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveTo evaluate patient-specific patellofemoral joint (PFJ) cartilage 3 years postoperatively using T2 mapping magnetic resonance imaging and the uninjured contralateral side as control. HYPOTHESIS: The cartilage of the PFJ in the anterior cruciate ligament (ACL) reconstructed knees would show increased T2 values compared to the uninjured contralateral knees at 3-year follow-up, and the femoral (trochlear) cartilage would be more susceptible than the patella in degeneration in ACL-reconstructed knees.
methodsTen patients with clinically successful ACL-reconstructed knees were prospectively enrolled 3 years postoperatively. Sagittal images of both knees were obtained using T2 mapping. Cartilage over the medial, central, and lateral regions of the trochlea and patella was divided into superficial and deep regions. Average T2 values of the cartilage at each region of interest of the ACL-reconstructed and uninjured contralateral knees were compared for each individual patient.
resultsOverall, the T2 values at the superficial layers of the medial and central trochlear cartilage of the ACL-reconstructed knees were significantly higher than those of the uninjured contralateral knees by 4.23 ± 9.09 milliseconds (8.9%;
conclusionDespite a clinically satisfactory ACL reconstruction (with negative anteroposterior drawer and pivot shift tests), all patients showed at least one region with increased T2 value of the PFJ cartilage 3 years after ACL reconstruction, especially at the medial compartment of the trochlear cartilage. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: Little data has been reported on PFJ cartilage condition after ACL reconstruction. This study could help develop noninvasive diagnostic methods for detection of early PFJ cartilage degeneration after ACL reconstruction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.