Evidence map›Paper›PMID 29662666›Full record

ArticleOncotarget2018

CD30 expression and survival in extranodal NK/T-cell lymphoma: a systematic review and meta-analysis.

Zihang Chen, Pujun Guan, Tong Shan, Yunxia Ye, Limin Gao, Zhi Wang, Sha Zhao, Wenyan Zhang, Li Zhang, Ling Pan and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Zihang ChenDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Pujun GuanHuaxi Magnetic Resonance Research Center, Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Tong ShanInstitute of Public Health, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Yunxia YeDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Limin GaoDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Zhi WangDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Sha ZhaoDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Wenyan ZhangDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Li ZhangDepartment of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Ling PanDepartment of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Weiping LiuDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Sichuan University · CNWest China Hospital of Sichuan University · CNNorthwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe paradoxical reports about the prognostic value of the CD30 expression in extranodal NK/T-cell lymphoma (ENKTL) have restricted its further applications in clinical practice. To identify the common effects and the variation, we conducted this systematic review and meta-analysis.

methodsPubMed, MEDLINE, Embase, and Web of Science were searched between January 1975 and 31 January 2017. The pooled hazard ratio was used to estimate the effect of the CD30 expression on overall survival. Bias was assessed by prespecified criteria referring to Reporting Recommendations for Tumor Marker Prognostic Studies and Newcastle-Ottawa Scale.

resultsTen retrospective cohort studies with 310 patients are included. CD30 is associated with better overall survival significantly (HR 0.71, 95% CI 0.51 to 0.99,

conclusionsThis study indicates that the CD30 expression is significantly associated with better prognosis in ENKTL, especially for patients with regional lymphoma involvement.

Indexed as

CD30extranodal natural killer/T-cell lymphomameta-analysisprognostic value

Identifiers

PMID29662666
PMCPMC5893261
OpenAlexW2783892908

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.