Evidence map›Paper›PMID 29662664›Full record

ArticleOncotarget2018

Regulation of the antiapoptotic protein cFLIP by the glucocorticoid Dexamethasone in ALL cells.

Lara Kleinesudeik, Katharina Rohde, Simone Fulda

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Lara KleinesudeikInstitute for Experimental Cancer Research in Pediatrics, Goethe-University, Frankfurt, Germany.
Katharina RohdeInstitute for Experimental Cancer Research in Pediatrics, Goethe-University, Frankfurt, Germany.
Simone FuldaInstitute for Experimental Cancer Research in Pediatrics, Goethe-University, Frankfurt, Germany.
Deutschen Konsortium für Translationale Krebsforschung · DEFrankfurt Cancer Institute · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently reported that the Smac mimetic BV6 and glucocorticoids, e.g. Dexamethasone (Dexa), synergize to induce cell death in acute lymphoblastic leukemia (ALL)

Indexed as

apoptosiscFLIPglucocorticoidSmac mimetic

Identifiers

PMID29662664
PMCPMC5893259
OpenAlexW2795051201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.