Evidence map›Paper›PMID 29662596›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2016

Single Nanoparticle Plasmonic Spectroscopy for Study of Charge-Dependent Efflux Function of Multidrug ABC Transporters of Single Live

Lauren M Browning, Kerry J Lee, Prakash D Nallathamby, Pavan K Cherukuri, Tao Huang, Seth Warren, Xiao-Hong Nancy Xu

Abstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lauren M BrowningDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Kerry J LeeDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Prakash D NallathambyDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Pavan K CherukuriDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Tao HuangDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Seth WarrenDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Xiao-Hong Nancy XuDepartment of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Old Dominion University · US

Funding

Nanoassay for Realtime Molecular Probing ABC TransporterR01GM076440 · NIGMS · OLD DOMINION UNIVERSITY · PI XU, X. NANCY · 2006 to 2010
$1.7M
New Photostable Nanoprobes for Real-time Imaging of Single Live CellsR15GM119116 · NIGMS · OLD DOMINION UNIVERSITY · PI XU, X. NANCY · 2016 to 2017
$555k
Photostable Multiplexing NanoAssays for Real-Time Study of Embryonic Stem CellsR21HL127580 · NHLBI · OLD DOMINION UNIVERSITY · PI XU, X. NANCY · 2015 to 2016
$426k
NHLBI NIH HHS R21 HL127580NIGMS NIH HHS R01 GM076440NIGMS NIH HHS R15 GM119116
6 · The paper itself

Abstract

Multidrug membrane transporters can selectively extrude a wide variety of structurally and functionally unrelated substrates, and they are responsible for ineffective treatment of a wide range of diseases (e.g., infection and cancer). Their underlying molecular mechanisms remain elusive. In this study, we functionalized Ag NPs (11 nm in diameter) with two biocompatible peptides (CALNN

Identifiers

PMID29662596
PMCPMC5899213
OpenAlexW2407380740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.